Hybrid Monoterpenoid Indole Alkaloids Obtained as Artifacts from Rauvolfia tetraphylla
Pourquoi ce travail est-il dans la base ?
Une base qui oublie comment elle a trouvé un travail ne peut pas être vérifiée. Voici les voies qui ont admis celui-ci.
Le tri à trois modèles
les 1 000 travaux triés →Les trois modèles l'ont jugé hors champ.
Natural products chemistry paper isolating indole alkaloid artifacts from Rauvolfia; the object is phytochemistry.
The paper reports the isolation and evaluation of natural products from a plant genus.
Natural-products chemistry of alkaloids from Rauvolfia.
Résumé
Rauvolfia genus of the Apocynaceae family, comprising about 60 species, is mainly distributed in America, Africa, Asia, and Oceania [ 1 ]. Plants of this genus are a rich source of monoterpenoid indole alkaloids, which have attracted great interests from biological and therapeutic aspects [ 2 – 5 ]. As part of a BioBioPha [ http://www.chemlib.cn ] objective to assemble a large-scale natural product library valuable in the discovery of new drug leads from nature, previous chemical study on the ethanolic extract of Rauvolfia tetraphylla had resulted in the isolation of five new indole alkaloids, rauvotetraphyllines A–E [ 6 ]. Further investigation of the remaining components led to the isolation of another five new alkaloids bearing an unusual 2,2-dimethyl-4-oxopiperidin-6-yl moiety, rauvotetraphyllines F–H ( 1 , 3 , 4 ), 17- epi -rauvotetraphylline F ( 2 ) and 21- epi -rauvotetraphylline H ( 5 ). The present paper describes the isolation, structure elucidation, and cytotoxic evaluation of the new compounds.
Conservé avec la notice de tri, où il sert de preuve aux étiquettes ci-dessus.
La notice
- Revue
- Natural Products and Bioprospecting
- Thématique
- Alkaloids: synthesis and pharmacology
- Domaine
- Pharmacology, Toxicology and Pharmaceutics
- Établissements canadiens
- Francophone University Association
- Organismes subventionnaires
- National Development and Reform Commission
- Mots-clés
- Indole testChemistryCytotoxicityIn vitroStereochemistryBiologyTraditional medicineBotanyBiochemistryMedicine
- Résumé présent dans OpenAlex
- oui