Childhood Maltreatment and Stress Sensitization in Depression: Moderation by Age Group and Depression History
Notice bibliographique
Résumé
Major Depressive Disorder is a highly prevalent and recurrent psychological disorder, affecting approximately 12% of Canadians across their lifetime and 5% each year.Studies have shown that a history of childhood maltreatment increases risk for depression by conferring a vulnerability to the effects of stressful life events (i.e., stress sensitization).The goal of the current investigation was to examine whether the relation between childhood maltreatment and stress sensitization in depression is influenced by age group and depression history.This study also sought to investigate whether specific characteristics of the maltreatment experience differentially relate to stress sensitization.Two hundred and seven clinically depressed adolescents (i.e., 12 -17 years; n = 59) and adults (i.e., 18 -64 years; n = 148) participated in this study.Childhood accounts of maltreatment were assessed using the Childhood Experience of Care and Abuse Scale, and stressful life events experienced 3-months prior to depression onset were assessed using the Life Events and Difficulties Schedule.Results revealed that individuals with a history of severe maltreatment reported lower severity levels of stressful life events prior to depression onset than did those without such a history, but only among adolescents.Further, this relation was specific to independent stressors (i.e., those totally or nearly totally independent of the behaviour of the individual) and not dependent stressors (i.e., those at least partly due to the individual's behaviour), and was specific to emotional abuse.Results also suggested that it is the experience of severe maltreatment, rather than particular aspects of it, that sensitizes individuals to the effects of stress.In summary, this study provides support for the relation of childhood maltreatment to stress sensitization in adolescents.Maltreated adolescents may be especially vulnerable to the depressogenic effects of stress, perhaps because their maltreatment experience is more proximal to iii depression onset.In contrast, other relevant processes (e.g., cognitive schema and neurobiological consolidation, chronic stress) may drive stress sensitization in adulthood; however, further research is required to investigate such mechanisms.Limitations and clinical implications are discussed.Harkness.Over the past two years, she has provided me with endless guidance and support.I am very grateful for the opportunity to learn from her and look forward to working together in the years to come.I would also like to thank my committee members, Dr. Ron Holden and Dr. Chris Bowie, for their contributions.Their comments and suggestions offered novel insight and helped to improve the final product.I am grateful to my fellow labmates, Jeremy Stewart and Dustin Washburn, who have provided so much inspiration and support over the past two years.Whether I needed someone to lean on or someone to celebrate with, they were always available and I cherish our friendship.I would also like to acknowledge the many exceptional and dedicated members of the Mood Research Lab.These individuals have contributed countless hours of data collection, entry, and emotional support, and this project would not have been possible without their help.I owe many thanks to my family and friends in Kelowna, Kingston, and everywhere in between.I am especially grateful for the continued support of those who have been there through the ups and downs of my university career.My parents, Dan and Mary, and my big sis, Danielle, have shown me unconditional love and support, even during my most neurotic moments.Dr. Jan Cioe has inspired me to believe in my abilities and take pride in my accomplishments, and I am
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,001 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».