ANALYSIS OF SUICIDAL ATTEMPTS INSCHIZOPHRENICS" N ASRAM HOSPITAL, ELURU
Notice bibliographique
Résumé
BACKGROUND AND OBJECTIVES Schizophrenia is a complex neurobehavioral disorder that appears to be closely associated with suicidal behavior. Suicide is a major cause of premature death among patients suffering from schizophrenia.The present study is carried to study the frequency of suicide attempts in persons with schizophrenia and to compare various clinical and socio demographic variables of patients suffering from schizophrenia with and without suicide attempts, in search of possible risk factors for suicide in schizophrenia. METHODOLOGY 100 consecutive patients suffering from schizophrenia based on ICD-10 diagnostic criteria,fulfilling inclusion and exclusion criteria, attending the outpatient department were studied using Semi-structured proforma, SAPS, SANS,CDSS,Beck’s Suicide intent scale and clinical interview.The study is a cross sectional descriptive study.Statistical analysis was done using the chi-square test and the unpaired t-test. RESULTS Out of 100 patients studied, 27% had attempted suicide(n=27). Individuals who had a family history of suicide,prominent positive symptoms and depressive features,who were in their early stages of illness(first few years), had more suicidal attempts compared to those who did not have. We did not find any significant association between the various demographic variables,subtype of illness,negative symptoms,duration of illness, and the suicidal behavior. CONCLUSIONS People suffering from schizophrenia are at a highrisk for making suicidal attempts, especially when the illness is acute and severe, in early stages, when accompanied by depressive symptoms. Early identification of risk factors and employment of possible preventive strategies,and effective monitoring of treatment would definitely make us keep a step towards meeting one of the greatest unmet challenges in psychiatry, “Suicide inSchizophrenia.” LIST OF ABBREVIATIONS CDSS Calgary Depression rating scale for schizophrenia D-FEN D fenfluramine DST Dexamethasone suppression test EEG ElectroEncephaloGraphy EPS Extrapyramidal symptoms 5-HTR Serotonin receptor 5-HTTgene Serotonin transporter gene IL-6 Interleukin 6 MAO A Monoamineoxidase A PRL Prolactin REM Rapid Eye Movement sleep SANS Scale for assessment of negative symptoms SAPS Scale for assessment of positive symptoms SNP Single nucleotide polymorphism TPH 1 Tryptophan hydroxylase1 gene INTRODUCTION Schizophrenia is a complex neurobehavioral disorder that appears to be closely associated with suicidal behavior. Schizophrenia is associated with an excess premature mortality, up to 40% of this excess premature mortality can be attributed to suicide and unnatural deaths1. Suicide is a major cause of premature death among patients suffering from schizophrenia2,3. It reduces the life expectancy of those afflicted by approximately 10 years. About 25% of schizophrenic patients make at least one suicide attempt in their lifetime People with schizophrenia are known to die much earlier than expected5.Lifetime suicide risk is 4.9% for people with schizophrenia6. Detection of those at risk is clinically important, but risk prediction is known to be imprecise7. Inskip et al performed a meta-analysis on suicide among patients with affective disorder, alcoholism, and schizophrenia, and estimated that the lifetime risk of suicide was 4% for schizophrenia an estimate for schizophrenia that is consistent with the estimate of Palmer et al10.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,003 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,002 | 0,002 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,001 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».