An evolving pattern of cardiovascular risk in 14,315 men and women attending a nurse-led, cardiac profiling and prevention clinic over a quarter of a century
Notice bibliographique
Résumé
Purpose: The burden of cardiovascular disease continues to evolve as the demographic and risk factor profile of affected populations changes over time. In order to document potentially important changes in primary prevention efforts in this regard, we examined the risk profile of >14,000 first time attendees to a nurse-led, cardiac profiling and prevention clinic over a 25-year period. Methods: Routine demographic and clinical data were collected, in a standardised manner, in 7815 men and 6500 women who visited the free and open public access clinic (located in a cardiology unit of a major tertiary hospital) during the period June 1986 to December 2011. Data were compared on a sex-specific basis according to five-yearly historical periods (1986-1991 [P1 - initial 6 months included], 1992-1996 [P2], 1997-2001 [P3], 2002-2006 [P4], 2007-2011 [P5]). Results: Overall, the age profile of men (45.2±14.9 vs. 53.2±14.6 years) and women (45.8±15.5 vs. 52.4±14.3 years) attending the clinic was similar but progressively older over time (P1 vs. P5). In men, average blood pressure (BP) reached a peak during P3 (135±18/84±11 vs. 131±16/83±10 mmHg in P1) before declining in P4/P5 and in women peaked during P4 (137±21/80±11 vs. 126±19/79±11mmHg in P1); p<0.001 for all comparisions. Men and women with elevated BP (≥140/90mmHg) peaked in P2 (46.6%) and in P4 (45%), respectively, but declined overall (39.5% to 31.7% and 28.2% to 24% for P1 vs. P5, respectively); p<0.001. In women there were only small changes in average lipid levels, while in men there was an overall fall from P1 to P5 (5.4±1.1 vs. 5.0±1.2 mmol/L; p<0.001). Men and women with elevated lipid levels (total cholesterol ≥5.5mmol/L) generally declined over time (41.8% to 30.8% and 40.3% to 32.1% for P1 vs. P5, respectively); p<0.001. The proportion of current male smokers initially declined (from 14.3% to 11.2% in P3) before rising again (14.4% in P5) and in women progressively declined from 13.3% to 10.4% (P1 to P5; p<0.001). Throughout the study period (P1 to P5) both men (79.1±11.8 vs. 84.7±15.7 kg) and women (63.6±11.1 vs. 70.7±15.6 kg) became progressively heavier; p<0.001. Fasting blood glucose levels peaked in P3 for both men and women (∼0.5mmol/L more than P1) before also declining towards P1 levels in P4/P5. Conclusions: Over 25 years or more of clinical experience, men and women being profiled for the prevention of cardiovascular disease via a nurse-led clinic have become older and heavier. Consistent with population trends, historical highs in BP and lipid levels have now passed, but risk levels (particularly metabolic-related) remain high.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,010 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».