Sexual Interest and Satisfaction in an Internet Cohort of Patients with Inflammatory Bowel Diseases
Notice bibliographique
Résumé
Although GI and other somatic symptoms, concerns about body image, medication side effects, and surgical treatments and ostomies may impair sexual functioning in patients with inflammatory bowel diseases (IBD), few studies have examined this. We sought to evaluate sexual interest and satisfaction in a large cohort of adult patients with IBD and identify clinical and demographic factors associated with these patient-reported outcomes. CCFA Partners is an ongoing internet cohort study of over 12,000 patients with IBD. We invited a randomly selected subset of the cohort to complete a six question supplemental survey regarding sexual interest and satisfaction, and whether IBD symptoms or ostomy (if applicable) affected sexual satisfaction. Measures were developed and validated as part of the NIH Patient Reported Outcome Measurement Information System (PROMIS) initiative. Demographic information, self-reported disease indices [Short Crohn's Disease Activity Index (SCDAI), Simple Clinical Colitis Activity Index (SCCAI), and Manitoba Index], the Short IBD questionnaire (SIBDQ) quality of life index, and additional PROMIS outcomes were also measured. We used descriptive statistics and bivariate comparisons to assess relationships between sexual interest and satisfaction and the other measures. A total of 2581 individuals completed the supplemental survey (32% opted out). Mean age was 42(SD = 14); 71% female. Of 2151 patients who reported active IBD symptoms, 80% indicated that their symptoms affected their sexual satisfaction and 33% indicated their symptoms affected their sexual satisfaction “quite a bit” or “very much”. Of 110 patients with an ostomy, equal numbers reported that their ostomy affected their satisfaction “not at all” or “a little bit” versus “quite a bit” or “very much”. On average, males had higher sexual interest and satisfaction than females (p < 0.001), while there was no difference in sexual interest or satisfaction among those with CD versus UC. Among CD patients, active perirectal disease was associated with lower levels of sexual interest and satisfaction. Sexual interest and satisfaction were both negatively associated with increasing disease activity as measured by SCDAI, SCCAI, and Manitoba Index and positively associated with higher levels of health-related quality of life as measured by SIBDQ (P < 0.001 for all comparisons). Sexual interest and satisfaction were both negatively associated with increasing levels of fatigue, anxiety, and depression. IBD patients are willing to respond to questions regarding their sexual interest and satisfaction, as indicated by the high response rate. IBD, particularly active disease, is associated with impaired sexual functioning. Only about half of patients with ostomies indicated that their ostomies affected sexual satisfaction. Providers should be aware that disease activity can affect sexual function and satisfaction, and counsel or screen appropriate patients.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,001 | 0,001 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,003 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».