2316 NONINVASIVE DIAGNOSIS OF BLADDER DYSFUNCTION IN PATIENTS WITH INTERSTITIAL CYSTITIS / PAINFUL BLADDER SYNDROME USING NEAR INFRARED SPECTROSCOPY
Notice bibliographique
Résumé
You have accessJournal of UrologyUrodynamics/Incontinence/Female Urology: Urodynamic Testing1 Apr 20122316 NONINVASIVE DIAGNOSIS OF BLADDER DYSFUNCTION IN PATIENTS WITH INTERSTITIAL CYSTITIS / PAINFUL BLADDER SYNDROME USING NEAR INFRARED SPECTROSCOPY babak shadgan, Lynn Stothers, and andrew macnab babak shadganbabak shadgan vancouver, Canada More articles by this author , Lynn StothersLynn Stothers vancouver, Canada More articles by this author , and andrew macnabandrew macnab vancouver, Canada More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.2497AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Painful bladder syndrome/interstitial cystitis (PBS/IC) is defined as a syndrome of urgency, frequency, and suprapubic pain in the absence of positive urine culture or obvious bladder pathology. As no specific etiology has been identified yet, no specific methodology exists for diagnosis of this condition. Diagnosis of PBS/IC is currently based on clinical judgment of treating urologist after ruling out other urinary pathologies, using invasive cystoscopic and urodynamic (UDS) studies. One potential etiology of PBS/IC is bladder mucosa inflammation associated with abnormal angiogenesis and ulcerative lesions in bladder mucosa. A method capable of evaluating bladder wall metabolism may therefore be relevant for diagnosis of PBS/IC. Near infrared spectroscopy (NIRS) is a noninvasive optical technique using light to monitor tissue oxygenation and hemodynamics. The purpose of this study was to examine ability of NIRS to differentiate subjects identified as PBS/IC from other marked bladder conditions. METHODS Twenty four adult patients with lower urinary tract dysfunction were devided into 2 groups, PBS/IC (4 male aged: 27.5±8 yrs) and non-PBS/IC (8 male and 12 female aged: 47.7±4.8 yrs) after standard diagnostic investigations. Detrusor oxygen saturation percentage (TSI%), a direct index of tissue metabolism, were studied in all subjects using a spatially-resolved (SR) NIRS instrument, simultaneous to UDS study. After one minute baseline measurement in supine rest position with empty bladder, the detrusor TSI% was recorded by the NIRS instument that was placed and fixed over the bladder. Statistical difference of the detrusor TSI% values between two groups were studied. RESULTS Mean resting values of detrusor TSI% were significantly different (P<0.0005) between 2 groups (74.2%±4.9 in PBS/IC vs. 63.6%±5.5 in non-PBS/IC). CONCLUSIONS Noninvasive NIRS interrogation of the bladder demonstrated significant increase in detrusor oxygen saturation in patients diagnosed as PBS/IC. This observation may support previous reports that indicated bladder mucosa inflammation associated with abnormal angiogenesis and ulcerative lesions in bladder mucosa as the main etiology of the PBS/IC. This study presents potential application of SR-NIRS for noninvasive diagnosis of PBS/IC. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e935 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information babak shadgan vancouver, Canada More articles by this author Lynn Stothers vancouver, Canada More articles by this author andrew macnab vancouver, Canada More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,002 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,001 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,013 | 0,003 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».