Concomitant Babesia gibsoni and Ehrlichia canis infection in a dog
Notice bibliographique
Résumé
Experimental transmission of Babesia gibsoni in a dog, in a state of subclinical infection by Ehrlichia canis, resulted in a severe concomitant infection of E. canis and B. gibsoni characterized by neurological signs, including nystagmus and seizures.Mononuclear cells harbouring the characteristic morulae of E. canis were numerous in lung impression smears.B. gibsoni were observed in the peripheral blood in erythrocytes and within macrophages in spleen, liver and kidney impression smears.Erythrocytes were found trapped within capillaries of the brain.B. gibsoni were seen in various stages of division and on average 16 merozoites were seen in a single infected erythrocyte. Key words: ehrlichiosis, babesiosis, dogVet. arhiv 75 (6), [513][514][515][516][517][518][519][520] 2005 in a dog that was in the subclinical phase of ehrlichiosis.It also focuses attention on the resultant syndrome caused by the mixed infection of E. canis and B. gibsoni. Materials and methodsAn isolate from a dog with naturally occurring canine ehrlichiosis diagnosed at the Madras Veterinary College Clinics was used.The dog had a history of tick infestation and had pyrexia and enlargement of popliteal lymph nodes.Microscopic examination of peripheral blood smears revealed the presence of Ehrlichial inclusions in mononuclear cells.Babesia gibsoni was isolated from a dog that was naturally infected with B. gibsoni, at the Madras Veterinary College Clinics.The dog was an intact, one-year-old male Labrador retriever with a history of exposure to ticks.The dog was pyrexic and had blanched conjunctival mucous membranes.Microscopic examination of peripheral blood smears revealed the presence of B. gibsoni piroplasms in RBC.The experimental dog was housed in a kennel with tick-proof conditions and was vaccinated against canine distemper, infectious canine hepatitis and leptospirosis.The dog was also treated with anthelmintic before its use in the experiment.Freedom from E. canis was confi rmed on the basis of negative results with ELISA and Dot-ELISA and freedom from haemoprotozoan infections was ascertained by thorough screening of peripheral blood smears for 10 days before being used in the experiment.Experiment I: Experimental dog aged about 6 months, seronegative for E. canis by ELISA and Dot-ELISA, was inoculated with fi ve ml of heparinized blood collected from a dog naturally infected with E. canis.Experiment II: The same dog was inoculated with 5 ml of B. gibsoni-infected blood after 90 days post-infection with canine ehrlichiosis.Sera were analyzed for E. canis antibodies by ELISA and Dot-ELISA using DH 82 cells infected with E. canis (Oklahoma strain).The sera were examined before and after experimental infection with E. canis.Antigen and known positive serum was provided by the Department of Infectious Diseases and Physiology, College of Veterinary Medicine,
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».