Bibliographic record
Abstract
Experimental transmission of Babesia gibsoni in a dog, in a state of subclinical infection by Ehrlichia canis, resulted in a severe concomitant infection of E. canis and B. gibsoni characterized by neurological signs, including nystagmus and seizures.Mononuclear cells harbouring the characteristic morulae of E. canis were numerous in lung impression smears.B. gibsoni were observed in the peripheral blood in erythrocytes and within macrophages in spleen, liver and kidney impression smears.Erythrocytes were found trapped within capillaries of the brain.B. gibsoni were seen in various stages of division and on average 16 merozoites were seen in a single infected erythrocyte. Key words: ehrlichiosis, babesiosis, dogVet. arhiv 75 (6), [513][514][515][516][517][518][519][520] 2005 in a dog that was in the subclinical phase of ehrlichiosis.It also focuses attention on the resultant syndrome caused by the mixed infection of E. canis and B. gibsoni. Materials and methodsAn isolate from a dog with naturally occurring canine ehrlichiosis diagnosed at the Madras Veterinary College Clinics was used.The dog had a history of tick infestation and had pyrexia and enlargement of popliteal lymph nodes.Microscopic examination of peripheral blood smears revealed the presence of Ehrlichial inclusions in mononuclear cells.Babesia gibsoni was isolated from a dog that was naturally infected with B. gibsoni, at the Madras Veterinary College Clinics.The dog was an intact, one-year-old male Labrador retriever with a history of exposure to ticks.The dog was pyrexic and had blanched conjunctival mucous membranes.Microscopic examination of peripheral blood smears revealed the presence of B. gibsoni piroplasms in RBC.The experimental dog was housed in a kennel with tick-proof conditions and was vaccinated against canine distemper, infectious canine hepatitis and leptospirosis.The dog was also treated with anthelmintic before its use in the experiment.Freedom from E. canis was confi rmed on the basis of negative results with ELISA and Dot-ELISA and freedom from haemoprotozoan infections was ascertained by thorough screening of peripheral blood smears for 10 days before being used in the experiment.Experiment I: Experimental dog aged about 6 months, seronegative for E. canis by ELISA and Dot-ELISA, was inoculated with fi ve ml of heparinized blood collected from a dog naturally infected with E. canis.Experiment II: The same dog was inoculated with 5 ml of B. gibsoni-infected blood after 90 days post-infection with canine ehrlichiosis.Sera were analyzed for E. canis antibodies by ELISA and Dot-ELISA using DH 82 cells infected with E. canis (Oklahoma strain).The sera were examined before and after experimental infection with E. canis.Antigen and known positive serum was provided by the Department of Infectious Diseases and Physiology, College of Veterinary Medicine,
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".