0469 Use of low-cost, non-nutritive adsorbents as intestinal binding agents to sequester the boar taint compound androstenone
Notice bibliographique
Résumé
Boar taint is an unpleasant odor and taste detected from pork of some intact males when cooked, caused by high accumulation of the testicular steroid androstenone and the indole skatole. Currently available research exploring dietary approaches to control androstenone is scarce. The objective of this study was to evaluate for the efficacy of binding agents in vivo against androstenone and its impacts on performance in intact male pigs, following up on previous works in vitro. The study aims to capitalize on a hormone-recycling phenomenon which takes place in the gastrointestinal tract of animals, called enterohepatic circulation. Four adsorbents have been assessed for their binding effectiveness against androstenone in our laboratory; these were previously used in studies which successfully mitigated negative effects associated with mycotoxin ingestion in production animals. All additives bound androstenone in high efficacies in vitro, which warranted evaluation of the effectiveness of these binders in swine diets to reduce its levels in plasma and fat. Ninety (n = 90) purebred Duroc boars (123 ± 6 d of age at start of experiment) were equally allocated (n = 18) and fed 1 of 4 diets added with 2% bentonite (BNT), 3.5% diatomaceous earth (DE), 15% spent filter aid (SFA), or 0.7% hydrated sodium-calcium aluminosilicate (HSCAS) for at least 28 d followed by 14 d of recovery. All groups were compared with a control entire male group (n = 18) fed a typical corn-soybean meal finisher diet. Plasma samples and backfat biopsies were collected at d 0, 14, 28, 42, and 56 of trial. Pigs were weighed weekly and calculated for growth performance parameters. Estrone-1-sulfate in plasma was analyzed as a positive control for enterohepatic circulation. Analysis of trends during the treatment period were performed using the PROC MIXED repeated measures procedure in SAS (SAS Institute, Cary, NC, USA). There were no differences in ADG, ADFI, or FCR across diets (P > 0.05) throughout the treatment period. In addition, there were no significant decreases in backfat or plasma androstenone and estrone-1-sulfate across pigs fed treatment diets by d 28 (P > 0.05). However, there was a wide variation in plasma and fat androstenone concentration, which may result from the process of transporting the pigs into a novel environment and mixing. Further research using of crossbred pigs that will not be mixed and/or transported into unfamiliar groups is needed to conclusively evaluate the efficacy of these treatments.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,002 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».