Frequency and predictors of hospitalization during chemotherapy: a systematic review.
Notice bibliographique
Résumé
6583 Background: Hospitalization during chemotherapy is a significant event from both the patient and healthcare system perspectives but little is known about how often it occurs and in which settings. We conducted a systematic review to define the frequency of and factors associated with treatment-related hospitalization among cancer patients (pts) undergoing chemotherapy. Methods: A systematic search of Medline and EMBASE databases, from 1946 to September 2013, was undertaken to identify articles reporting rates of hospitalization in pts with cancer undergoing chemotherapy. Observational studies and clinical trials were eligible but results were analysed separately for each group. Summary statistics were used to describe the results and the Chi-square test was used to compare the groups. Results: Sixty articles met inclusion criteria: 44 observational studies comprising 189,342 pts and 16 randomized controlled trials comprising 13,086 pts. The majority of articles (80%) focused on chemotherapy given with palliative intent most commonly in breast, lung and colorectal cancers. The proportion of pts hospitalized at least once was significantly higher in observational studies at 32% (range 27-38%) compared with 21% (range 15-27%) in randomized trials (OR 2.13, 95%CI 2.03-2.23, p < 0.0001). A significant difference was seen in both the adjuvant and palliative settings between real life and trial pts with 42 vs 16% (OR 2.94, 95%CI 2.72-3.18, p < 0.0001) of adjuvant and 33 vs 23% (OR 3.24, 95%CI 3.03-3.48, p < 0.0001) of palliative pts being hospitalized, respectively. Factors associated with hospitalization in observational studies included higher comorbidity, type of chemotherapy and geographic location, while performance status and type of chemotherapy were significant predictors in clinical trials. Age was not a risk factor in either population. A number of methodological issues regarding reporting of hospitalization parameters were identified such as poor definitions of the at-risk period and attribution of hospitalization as treatment-related. Conclusions: Hospitalization during chemotherapy is common especially in unselected patient populations. However, few articles report this and often do so poorly.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,002 | 0,003 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».