Shifting the limits in wheat research and breeding using a fully annotated reference genome
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Résumé
An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.
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La notice
- Revue
- Science
- Thématique
- Wheat and Barley Genetics and Pathology
- Domaine
- Agricultural and Biological Sciences
- Établissements canadiens
- Agriculture and Agri-Food CanadaPlant Biotechnology InstituteDefence Research and Development CanadaGlobal Institute for Water SecurityUniversity of Saskatchewan
- Organismes subventionnaires
- Bayer CropScienceNational Institute of Food and AgricultureDirectorate for Biological SciencesSaskatchewan Wheat Development CommissionJunta de AndalucíaGenome PrairieCanada First Research Excellence FundNorges Miljø- og Biovitenskapelige UniversitetRussian Science FoundationBiotechnology and Biological Sciences Research CouncilInstitut National de la Recherche AgronomiqueUniversität ZürichNorges ForskningsrådMinistry of Agriculture, Forestry and FisheriesConsiglio per la ricerca in agricoltura e l’analisi dell’economia agrariaAustralian GovernmentAgence Nationale de la RechercheMinistry of Agriculture - SaskatchewanGenome CanadaMinisterio de Asuntos Económicos y Transformación Digital, Gobierno de EspañaDeutscher Akademischer AustauschdienstRIKENTokyo University of AgricultureCentre of Excellence in Plant Energy Biology, Australian Research CouncilGerman Network for Bioinformatics InfrastructureBundesministerium für Ernährung und LandwirtschaftLeibniz-GemeinschaftTel Aviv UniversityGrantová Agentura České RepublikyGordon and Betty Moore FoundationWestern Grains Research FoundationEuropean CommissionDeutsche ForschungsgemeinschaftGrains Research and Development CorporationU.S. Department of AgricultureCanadian Light SourceAgriculture and Agri-Food CanadaNational Science Foundation
- Mots-clés
- GenomeBiologyReference genomeComputational biologyGeneGeneticsBiotechnology
- Résumé présent dans OpenAlex
- oui