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MORGEN & Data Release Policies: An Overview

2007· article· en· W2992464475 sur OpenAlexvenueaboutno aff
Cheryl Power

Notice bibliographique

RevueHealth law review · 2007
Typearticle
Langueen
DomaineBiochemistry, Genetics and Molecular Biology
ThématiqueCRISPR and Genetic Engineering
Établissements canadiensnon disponible
Organismes subventionnairesnon disponible
Mots-clésCommercializationScience policyComputer sciencePolitical sciencePublic administrationLaw
DOInon disponible

Résumé

récupéré en direct d'OpenAlex

1. Abstract In this paper I preliminarily examine Genome Canada's data release policy, (1) and patenting as a form of data release. Through a summary of several interesting case studies, I illustrate a sample of data release approaches that are currently in use by various consortia. I note that Genome Canada through their policy continues to try and strike a balance between the values of science and commercialization. For instance, data release policies in general have different impacts, one being the active free flow of scientific information. As well, there are a range of concerns about publicly disclosing such information and how effective these measures actually are when we think about long term goals surrounding translation and commercialization. 2. Introduction The MORGEN (2) G[E.sup.3]LS team is looking at the implications of data release policies in general, as well as specifically upon the products of genomic research, for the MORGEN project. The MORGEN project includes a study of the regulation of gene expression and how it specifies organogenesis, through studying development of the heart, liver and pancreas in the mouse embryo. This project follows on a previous project, the Mouse Atlas of Gene Expression, that deposited research results to a website. (3) Many such policies have emphasized the need for specific tailoring of data release for areas such as gene expression analysis. The Genome Canada data release policy specifically applicable to the MORGEN project notes a range of potential avenues for data release including: publishing; patents; researcher's publicly and freely accessible sources (website); data archives; open source archives; and depositing into strain collections. In order to better understand the alternatives provided by Genome Canada, we are also considering several policies set forth by other funding agencies. 3. Patenting as a form of Data Release Patenting is listed as a form of data release. The Genome Canada data release policy states that data must be released no later than the date that the patent (including provisional patents) has been applied for, and there is a provision to apply for delays beyond this. As such, patenting as a form of data release is actually keyed toward the actual application/provisional stage rather than the stage of issued patent. In this respect, there is a difference between the Genome Canada policy and the policy of similar funding agencies. In Genome Canada's policy, you can patent if you want, and there are delay possibilities built in to let you delay the release of data beyond the time of patent application. As well, if you are a proponent of the open science ideals, you can simply release to the public domain. In contrast to Genome Canada, the NIH Data Sharing Policy (4) does not call patenting a form of data release and puts clear limits on delays. Several timely examples of data release that our group is in the process of developing further are summarized in the following. 4. Potential Case Studies: Patenting & Data Release MORGEN: One form of data release used by the MORGEN project is depositing data to a publicly available website. MORGEN's website uses a Creative Commons (5) attribution 2.5 license. This license only provides copyright protection and does not protect any patent rights. Before disclosing to a publicly available website without first filing a provisional or a full patent, a number of issues surrounding disclosures and patentability must be considered. SARS: The patenting of the SARS virus has arguably been held out as an example of preserving access to genetic materials via the patent system. Provisional patents were filed by University of Hong Kong, the U.S. Centers for Disease Control and Prevention, and the British Columbia Cancer Agency [BCCA]. (6) In the context of BCCA's situation, a provisional patent was filed and data was also released to a publicly available website. …

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction distillée sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.

score de la tête « metaresearch » (Codex)0,001
score de la tête « metaresearch » (Gemma)0,000
Version: codex-gemma-dda1882f352aStatut de validation: machine_predicted_unvalidated
Catégories candidatesaucune
Catégories consensuellesaucune
DomaineSignal candidat: aucune · Signal consensuel: aucune
Devis d'étudeSignal candidat: Sans objet · Signal consensuel: aucune
GenreSignal candidat: Synthèse · Signal consensuel: Synthèse
Score de désaccord entre enseignants0,799
Score d'incertitude au seuil0,491

Scores Codex et Gemma par catégorie

CatégorieCodexGemma
Métarecherche0,0010,000
Méta-épidémiologie (sens strict)0,0000,000
Méta-épidémiologie (sens large)0,0000,000
Bibliométrie0,0000,000
Études des sciences et des technologies0,0000,000
Communication savante0,0000,000
Science ouverte0,0000,000
Intégrité de la recherche0,0000,000
Charge utile insuffisante (le modèle a refusé de juger)0,0000,000

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,090
Tête enseignante GPT0,472
Écart entre enseignants0,382 · la distance entre les deux têtes enseignantes sur ce seul travail
Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.

Les modèles n’ont appliqué aucune catégorie : rien dans la taxonomie ne correspondait à ce travail.
Devis d'étudeSans objet
Domainenon disponible
GenreSynthèse

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations0
Publié2007
Routes d'admission2
Résumé présentoui

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