OWE-36 Prevalence and factors associated with impaired food-related quality of life in 1223 people with IBD
Notice bibliographique
Résumé
<h3>Introduction</h3> Inflammatory bowel disease (IBD) patients often report that dietary intake and the enjoyment of food is affected by their condition. However, the prevalence of impaired food-related quality of life (FR-QoL) and associated factors have not been previously explored. This study aimed to determine the levels of FR-QoL and factors associated with it in a large, nationally representative sample of people with IBD. <h3>Methods</h3> A convenience sample of 1576 IBD outpatients ≥16 years old were recruited from seven UK centres. Patients consuming the majority of their intake as food completed previously validated questionnaires to capture demographic data, FRQoL-29, quality of life (IBDQ UK), IBD-distress (IBD-DS), IBD-fatigue (IBD-F), and anxiety and depression (HADS). A health professional recorded disease activity (HBI, SCCAI), disease classification (Montreal), blood results, body mass index and malnutrition risk (MUST). FR-QoL was regressed onto the explanatory variables (univariable/multivariable) using the Stata MI (20 imputed datasets) procedure. <h3>Results</h3> Data from 1223 patients were available (78% response, 65% CD and 51% female). FR-QoL mean score was 80.1 [SD 26.9] (minimum 29, maximum 145, higher score = better FR-QoL), considerably lower in comparison to previously measured healthy volunteers [123.0, SD 16.5]. The four items rated as the most severe (Strongly agree/Agree) were ‘avoiding food and drink I know does not agree with my IBD’ (71%), ‘being more aware of what I am eating due to my IBD’ (70%), ‘certain foods have triggered symptoms of my IBD‘ (69%) and ‘enjoyment of a particular food or drink has been affected by the knowledge that it might trigger my IBD symptoms’ (67%). Twenty-six factors (demographic, clinical, drug-related, psycho-social) were significantly associated with impaired FR-QOL in univariate analysis. However, in the multivariable regression only lower educational level (p<.001), greater number of IBD flares in last two years (p<.001), more severe symptoms during last flare (p=.034), not taking immune suppressants (p=.026), greater distress (p<.001), greater fatigue impact on daily living (p=.025) and worse IBD QoL (p<.001) remained significantly associated with impaired FR-QoL. <h3>Conclusions</h3> In this first large study reporting FR-QoL in IBD, many factors were identified as having a significant negative effect on patients with IBD. Understanding the relationship between IBD and FR-QoL may improve communication between health professionals and patients regarding its impact.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».