OWE-36 Prevalence and factors associated with impaired food-related quality of life in 1223 people with IBD
Bibliographic record
Abstract
<h3>Introduction</h3> Inflammatory bowel disease (IBD) patients often report that dietary intake and the enjoyment of food is affected by their condition. However, the prevalence of impaired food-related quality of life (FR-QoL) and associated factors have not been previously explored. This study aimed to determine the levels of FR-QoL and factors associated with it in a large, nationally representative sample of people with IBD. <h3>Methods</h3> A convenience sample of 1576 IBD outpatients ≥16 years old were recruited from seven UK centres. Patients consuming the majority of their intake as food completed previously validated questionnaires to capture demographic data, FRQoL-29, quality of life (IBDQ UK), IBD-distress (IBD-DS), IBD-fatigue (IBD-F), and anxiety and depression (HADS). A health professional recorded disease activity (HBI, SCCAI), disease classification (Montreal), blood results, body mass index and malnutrition risk (MUST). FR-QoL was regressed onto the explanatory variables (univariable/multivariable) using the Stata MI (20 imputed datasets) procedure. <h3>Results</h3> Data from 1223 patients were available (78% response, 65% CD and 51% female). FR-QoL mean score was 80.1 [SD 26.9] (minimum 29, maximum 145, higher score = better FR-QoL), considerably lower in comparison to previously measured healthy volunteers [123.0, SD 16.5]. The four items rated as the most severe (Strongly agree/Agree) were ‘avoiding food and drink I know does not agree with my IBD’ (71%), ‘being more aware of what I am eating due to my IBD’ (70%), ‘certain foods have triggered symptoms of my IBD‘ (69%) and ‘enjoyment of a particular food or drink has been affected by the knowledge that it might trigger my IBD symptoms’ (67%). Twenty-six factors (demographic, clinical, drug-related, psycho-social) were significantly associated with impaired FR-QOL in univariate analysis. However, in the multivariable regression only lower educational level (p<.001), greater number of IBD flares in last two years (p<.001), more severe symptoms during last flare (p=.034), not taking immune suppressants (p=.026), greater distress (p<.001), greater fatigue impact on daily living (p=.025) and worse IBD QoL (p<.001) remained significantly associated with impaired FR-QoL. <h3>Conclusions</h3> In this first large study reporting FR-QoL in IBD, many factors were identified as having a significant negative effect on patients with IBD. Understanding the relationship between IBD and FR-QoL may improve communication between health professionals and patients regarding its impact.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".