Cognitive impairment in patients with minor stroke/TIA: a follow-up study
Notice bibliographique
Résumé
Objective To investigate the changes of cognitive impairment with disease progression in patients with minor stroke/transient ischemic attack (TIA). Methods Consecutive patients with minor stroke/TIA were enrolled prospectively. Montreal Cognitive Assessment (MoCA) was used to conduct the cognitive function assessment within 7 d of the onset (baseline), at 1 and 3 months, respectively. Compared with the baseline, the total scores of MoCA in patients increased by ≥2 at 3 months were cognitive function improvement and increased <2 were no cognitive function improvement. Multivariate logistic regression analysis was applied to identify the independent risk factors for no cognitive improvement. Results A total of 112 patients with minor stroke/TIA were enrolled in the study, including 63 patients (56.2%) with TIA and 49 (43.8%) with minor stroke. At baseline, 1 month, and 3 months, 77 (68.8%), 72 (64.3%) and 60 (53.6%) patients had cognitive impairment. At 3 months after the onset, the cognitive function of 25 patients (22.3%) were improved, in which 19 (76.0%) and 6 (24.0%) patients had TIA/minor stroke respectively; 87 (77.7%) did not have any improvement. Compared with the improvement group, the level of education was significantly lower (3.29±3.48 years vs. 5.63±4.26 years; t=2.814, P=0.006), the level of glycosylated hemoglobin was significantly higher (6.35%±1.26% vs. 7.21%±1.26%; t=-3.088, P=0.003) in the no improvement group, and the proportions of patients with minor stroke (49.4% vs. 24.0%; χ2=5.101, P=0.024), hypertension (52.9% vs. 24.0%; χ2=6.509, P=0.011), hyperlipidemia (51.7% vs. 24.0%; χ2=6.019, P=0.014), diabetes (41.4% vs. 16.0%; χ2=5.448, P=0.020), and coronary heart disease (32.2% vs.8.0%; χ2=5.792, P=0.016) were significantly higher. Multivariate logistic regression analysis showed that the level of education (odds ratio [OR] 1.364, 95% confidence interval [CI] 1.059-1.756; P=0.016), atrial fibrillation (OR 2.509, 95% CI 1.020-6.167; P=0.045), and higher glycosylated hemoglobin level (OR 1.586, 95% CI 1.021-2.034; P=0.030) were the independent risk factors for no cognitive function improvement at 3 months after the onset of minor stroke/TIA. As time went on, the MoCA score and visual spatial execution, memory, abstract and directional scores were increased significantly (P<0.001), while there were no significant differences in naming, attention, and language scores. Conclusions About 2/3 patients with minor stroke/TIA had cognitive impairment, and as time went on, they were improved. The lower education level, atrial fibrillation and higher baseline glycated hemoglobin were the independent risk factors for affecting no cognitive impairment improvement after monor stroke/TIA. Key words: Stroke; Brain Ischemia; Ischemic Attack, Transient; Cognition Disorders
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».