Effects of hyperbaric oxygen on the cognition of the patients with stroke during the acute stage of cerebral infarction
Notice bibliographique
Résumé
Objective To investigate the effects of hyperbaric oxygen (HBO) on the cognition of the patients with stroke during the acute stage of cerebral infarction. Methods Ninety-four patients with acute cerebral infarction hospitalized in the department of the hospital from January to March, 2017 were enrolled for the study. A randomized controlled study was performed and the patients were randomly divided into 2 groups. During hospitalization, the treatment group was treated with HBO in addition to conventional treatment for cerebral infarction, while the control group was just given conventional therapy for cerebral infarction. National Institutes of Health Stroke Scale (NIHSS) scores and MoCA scores were assessed at time of admission. After 6 months of follow-ups, 4 patients with recurrent cerebral infarction or death or without medical follow-ups were excluded from the study, and the remaining 90 were included in the study. NIHSS scores, MoCA scores and mRS scores were calculated once again for the study. General medical data and scores were compared between the groups. Logistic regression was used to identify independent influential factors of cognitive impairment after stroke. Results There was no statistical significance in general medical data and various scores detected at the time of admission, when comparisons were made between the 2 groups. Six months after onset, statistical significance could neither be seen in NIHSS scores and the rate of good outcome, as compared with those of the control group. However, incidence of cognitive impairment after stroke was significantly lower than that of the control group(26.7% vs 48.9%)(P<0.05). Six months after onset, the MoCA scores were significantly lower than those of the control group, with statistical significance (27.3±1.52 vs 26.2±1.95) (P<0.05). Six months after onset of cerebral infarction, the scores of visual space/executive function and memory in the HBO group were considerably higher than those in the control group [4(4, 5)vs 4(4, 4)] (P<0.05). Logistic regression analysis revealed that education background (OR=0.711, 95% CI 0.556-0.910) (P=0.007), homocysteine (OR=1.271, 95% CI 1.015-1.591)(P=0.037) and leukoaraiosis (OR=2.854, 95% CI 1.327-6.147) (P=0.007) were independent factors of cognitive impairment after stroke, and whether not to choose HBO therapy was not an independent factor of cognitive impairment after stroke. Conclusion HBO therapy during the acute stage of cerebral infarction seemed to have little effect on the prognosis of the impairment 6 months after onset. However, it could significantly reduce the incidence of cognitive impairment after stroke and improve the visual spatial/executive function and memory. Key words: Hyperbaric oxygen; Stroke; Cognition
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Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».