046 Feasibility, Acceptability and Effects of Physical Therapy Treatment for Gynecological Cancer Survivors with Dyspareunia
Notice bibliographique
Résumé
Dyspareunia affects more than half of gynecological cancer survivors. These women are confronted with this serious health issue as well as relationship difficulties and psychological distress. Despite the impact on their quality of life, the available treatments remain limited and poorly studied. Physical therapy (PT) has been shown to be highly effective to treat dyspareunia in younger populations with no history of cancer. However, no study has investigated PT in gynecological cancer survivors with dyspareunia. The main goal of this single-arm pilot study was to evaluate the feasibility and acceptability of a 12-week PT treatment in gynecological cancer survivors with dyspareunia. Secondary goals included examining the effects of PT in terms of frequency of sexual activities, pain quality and intensity, sexual function, sexual distress as well as patient’s satisfaction and global impression of change. Women who had completed treatment for a gynecological malignancy for at least 3 months, and were considered cured, were eligible to participate if they reported vulvovaginal pain at an intensity of ≥5 on a numerical rating scale (NRS: 0-10), for at least 80% of sexual intercourse attempts, for more than 3 months. The treating gynecologic oncologist performed a standardized pelvic and rectal examination to confirm eligibility. PT treatment consisted of 12 weekly 60-minute individual sessions including education, pelvic floor muscle exercises with biofeedback, manual therapy and home exercises. Attendance rate (proportion of sessions attended) and adherence rate (proportion of completed home exercises according to a diary) were calculated to describe feasibility and acceptability, as primary outcomes. Secondary outcomes concerning treatment effects were collected at baseline and post-treatment by a physical therapist not involved in patient’s care. They included frequency of sexual activities with vaginal penetration (number per month), pain quality (McGill Pain Questionnaire; minimal clinically important difference (MCID) -30%) and intensity (NRS; MCID -2), sexual function (Female Sexual Function Index; MCID +2.1) and sexual distress (Female Sexual Distress Scale-Revised; MCID -7). Level of satisfaction with treatment (NRS: 0-10) and Patient Global Impression of Change (PGIC 7-point scale: very much improved to very much worse) were also used. Paired t-tests or Wilcoxon signed-rank tests were conducted in conformity to data distribution to investigate the changes from baseline to post-treatment.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,004 | 0,014 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,001 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,001 | 0,001 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,007 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».