S0246 Anal Cancer: Overview of Hospitalizations, Healthcare Utilization, and Outcomes from the Inpatient World
Notice bibliographique
Résumé
INTRODUCTION: Anal cancer is an uncommon type of gastrointestinal malignancy that occurs in the anal canal and potentially cause signs and symptoms such as rectal bleeding and anal pain. Limited epidemiological data exist on cost of care and outcomes for hospitalizations with anal cancer. METHODS: National Inpatient Sample (NIS) database was analyzed during the period from 2001 to 2011 for all subjects with the diagnosis of anal cancer (ICD-9 code 154.3) as primary or secondary diagnosis. Nationwide Inpatient Sample (NIS) is the largest inpatient care database in the United States. Its large sample size is ideal for developing national and regional estimates. Cochran-Armitage trend test was used for determining statistical significance of variation. RESULTS: In 2001, there were 2,943 hospitalizations with anal cancer as compared to 5,587 in 2011 (P < 0.0001, Figure 1A). Age group 50–64 remained the most commonly affected with rising proportional trend from 32.5% in 2001 to 41.0% in 2011 (P < 0.0001, Figure 1B). Throughout the study period, more women (about two thirds each year) were hospitalized with anal cancer as compared to men (P < 0.0001, Figure 1C). Caucasians remained the most commonly affected race with a slight decrease in proportional trend from 78.4% in 2001 to 74.5% in 2011 (P < 0.0001). Southern US remained to have more anal cancer-related hospitalizations as compared to other regions, however, over the study period there was a decline in hospitalization rate from 44.7% in 2001 to 38.8% in 2011 (P < 0.0001). In- hospital mortality decreased from 3.2% in 2001 to 2.7% in 2011 (P < 0.0001) and average length of stay increased from 6.5 days in 2001 to 7.4 days in 2011 (P = 0.63). Cost per hospitalization increased from $10,749 in 2001 to $15,394 in 2011 (adjusted for inflation, P < 0.0001, Figure 1D). Analysis of the Agency for Healthcare Research and Quality (AHRQ) comorbidity measures revealed hypertension, fluid & electrolyte disorders, and deficiency anemias as some of the more commonly associated comorbidities with metastatic cancer showing increasing association over time (Figure 2).Figure 1Figure 2CONCLUSION: Significant rise in the number of hospitalizations with anal cancer was found with interesting demographic variations and association with comorbidities. Although in-hospital mortality decreased, there was a noteworthy rise in the cost of care. Further studies are needed to identify potential predictors & factors responsible for such results to better elucidate our findings.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».