Commentary: Coronavirus disease 2019 and acute aortic dissection: So many questions, so few answers
Notice bibliographique
Résumé
Central MessageCOVID-19 has complicated patient care in acute aortic dissection, requiring a thoughtful team approach that is individualized for each patient.See Article page 50. COVID-19 has complicated patient care in acute aortic dissection, requiring a thoughtful team approach that is individualized for each patient. See Article page 50. The coronavirus disease 2019 (COVID-19) pandemic has challenged our ability to deliver safe, timely, and high-quality care for our patients with acute aortic dissection while protecting our highly specialized aortic team members. The pandemic has influenced the clinical, educational, and administrative activities of cardiac surgery units globally. Furthermore, our ability to effectively treat patients has been severely affected. This has translated into a dramatic reduction in elective aneurysm repairs and increased wait times with consequent potential harm to patients. The pandemic has also affected urgent surgical care: We suspect that patients have avoided seeking hospital care due to fear of acquiring COVID-19, resulting in reduced demand for emergency dissection repair. This is corroborated by an increase in the number of patients dying out of hospital, and an overall excess mortality seen in several jurisdictions during the pandemic not directly attributable to COVID-19 infections.1El-Hamamsy I. Brinster D.R. DeRose J.J. Girardi L.N. Hisamoto K. Imam M.N. et al.The COVID-19 pandemic and acute aortic dissections in New York: a matter of public health.J Am Coll Cardiol. 2020; 76: 227-229Crossref PubMed Scopus (43) Google Scholar Murana and colleagues2Murana G. Folesani G. Botta L. Di Marco L. Leone A. Loforte A. et al.The effect of the coronavirus disease 2019 lockdown on type A acute aortic dissection: insights from Bologna.J Thorac Cardiovasc Surg Tech. 2020; 4: 50-54Scopus (3) Google Scholar from Bologna share their heroic experience with managing patients with acute aortic dissection early during the first wave of the pandemic through a national lockdown. They report patient avoidance behaviors causing delays in diagnosis, late presentations with malperfusion, and several patients who died before undergoing definitive repair. They were fortunate to have rapid testing protocols to confirm COVID-19 negative status on all patients undergoing operations who ultimately had very good outcomes with surgical repair. Although the authors observed pulmonary infiltrates on preoperative computed tomography scans that were concerning for COVID-19 in 30% of their patients, none of them tested positive for COVID-19. Patients with acute aortic dissection will remain a challenging group to treat during this ongoing pandemic. Timely access to emergency surgical care remains a life-saving priority; however, several considerations need to be made.•Rapid point-of-care COVID-19 testing should be systematically implemented to guide decision making for emergency operations and protect the surgical team and determine personal protective equipment requirements. COVID–19-positive patients undergoing cardiovascular surgery have an extremely high risk for perioperative death3COVIDSurg CollaborativeMortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study.Lancet. 2020; 396: 27-38Abstract Full Text Full Text PDF PubMed Scopus (1237) Google Scholar and anecdotal reports of acute dissection repair suggest similarly poor outcomes.•When taking a COVID–19-positive or suspect patient to the operating room for acute type A aortic dissection repair, operative expedience is likely paramount. Strategies to simplify surgical repair and minimize circulatory arrest and myocardial ischemic times should be considered. In this scenario, the primary focus must be on perioperative survival, even at the cost of late reoperation.•Lastly, if patients are COVID–19-positive, it would be wise to discuss the likelihood for postoperative respiratory failure and the potential need for aggressive respiratory support, including prolonged mechanical ventilation, tracheostomy, proning, and extracorporeal membrane oxygenation. Palliation may be considered in patients who are COVID-19 positive with extremely high-risk features (eg, octogenarians and patients with malperfusion syndrome) or hemodynamic instability. Patients with acute aortic dissection remain challenging at the best of times. COVID-19 has complicated patient care significantly, requiring a very careful and thoughtful team approach that is individualized for each patient, considering local pandemic activity and resources. These patients deserve our very best efforts, while balancing the needs of the pandemic as a whole. The effect of the coronavirus disease 2019 lockdown on type A acute aortic dissection: Insights from BolognaJTCVS TechniquesVol. 4PreviewItaly was among the first countries dealing with the spread of the coronavirus disease 2019 (COVID-19) pandemic, with more than 200,000 positive cases and about 27,000 deaths at the end of April 2020.1 According to the rapid surge in the number of cases, the Italian government imposed, from March 9 to May 4, 2020, specific mobility restrictions (ie, lockdown). Full-Text PDF Open Access
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,001 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,002 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».