Quantitative trait loci analysis for standard length and body weight in multi-families of mirror carp( Cyprinus carpio)
Notice bibliographique
Résumé
Common carp( Cyprinus carpio) is one of the most widespread freshwater teleost species in the world. It has been cultured as an important food fish worldwide,especially in China,for several thousand years. In the past decade,much research efforts have been made for the molecular breeding of common carp including development of polymorphic markers,linkage mapping,and quantitative trait loci( QTL) analysis.However,QTL researches of common carp have been limited by single family and small population size.Considering the ability to detect and identify QTL in single family is often limited and has obtained false positive locus. We conducted a whole genome scan on 522 progeny from 8 full-sib families using 250 microsatellites selected from high density genetic linkage map of common carp constructed by our lab. The genetic maps were constructed by use of the Cri-map program with genotypes of 8 families,and genetic distances were estimated by use of the Kosambi map function. A total of 233 markers were organized to 47 linkage groups and the linkage maps covered a genetic distance of 3 131. 5 cM,with the average interval for markers within linkage group of 16. 8 cM. The linkage map could be used for primary QTL analysis. QTL identification of standard length( SL) and body weight( BW) traits was carried out using half-sib mapping strategies by GridQTL software. We obtained 4 QTL distributed across 3 linkage groups( LG) during sirebased QTL analysis. For SL,3 QTL were identified,of which 1 QTL occurred at the 95% genome-wide level,and was located on LG24,accounting for 20. 3% of phenotype variation. The remaining 2 QTL were at the 95% chromosome-wide level,explaining 11. 9%( LG6) and 11. 6%( LG30),respectively. For BW,1QTL was identified at 99% genome-wide level,explaining 38. 3% of phenotypic variance and overlapped with the SL QTL intervals on LG24. During dam-based QTL analysis,we identified 8 QTL that were distributed across 5 LGs. Five QTL were associated with SL,of which one was at 99% chromosome-wide level and located at LG8. The other 4 QTL were at the 95% chromosome-wide level,accounting for 9. 6%-20. 3% of phenotypic variance. QTLs on LG24 and LG30 were significant both the sire and the dam-based analysis. For BW,three QTL were detected and have a similar confidence interval with SL at LG24,LG30 and LG45. Among these,2 QTL were identified at the 99% chromosome-wide level,and 1 QTL at the 95%chromosome-wide level,explaining 10. 8%-14. 1% of phenotypic variance. The results showed that the most significant QTLs for SL and BW were located on LG24 and common to both sire and dam. The results of this study not only can supply more reliable markers for molecular breeding of common carp,but also provide reference data for exploring regularity of QTL variation among different populations and families.
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Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,001 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».