The Effects of Physical Activity and Omega 3 Fatty Acids on Glucose Levels and Neuropathy Symptoms in Hispanic Diabetics in the “En Balancé Plus” Study
Notice bibliographique
Résumé
Background Diabetes is an important global public health burden. In the U.S., 8.3% of the population (i.e. 25.8 million individuals) have diabetes. Hispanic Americans have a higher prevalence of diabetes at 11.8% compared to non‐Hispanic whites. People with type‐2 diabetes often have developed an intolerance to insulin. For these individuals, healthy dieting and exercise, insulin therapy and proper medication will help to control and treat their diabetes. If not treated early, then diabetes affects many major organs, including the heart, blood vessels, nerves, eyes and kidneys. Controlling blood sugar levels can help prevent these complications. Aerobic and resistance exercise have been shown to be the most effective exercise regimen for diabetics to reduce neuropathy symptoms and lower glycemic levels, and slow down the damage to other organs. Omega 3 fatty acids have been shown to be effective in decreasing glucose levels as well. The purpose of this study was to assess the effects of physical activity and omega 3 fatty acid intake on the hemoglobin A1C levels and neuropathy symptoms in Hispanic diabetic patients. Methods Prospective three‐month study with 40 participants (male=16, female= 24). To evaluate the physical activity, participants were surveyed using the Arizona Physical Activity Frequency questionnaire at baseline and three months. The pain intensity of the participants was measured at baseline and three month using the short form of the McGill pain questionnaire which displayed a pain diagram. Both questionnaires were administered in Spanish. A 12‐hour fasting was required for the blood glucose concentration and lipid profiles which were analyzed. The fasting glucose levels and hemoglobin A1C levels were evaluated at the blood draw clinic and later analyzed at the Loma Linda University Medical Center. The participants attended a total of six nutritional and exercise classes conducted in Spanish for a total contact time of approximately 12 hours. The participants were followed up at 3 months. This case‐only design was funded by NIH and approved by the Loma Linda University Institutional Review Board (IRB). Results There was a significant reduction in Hb A1C level (mean= −0.55%, p=0.01), neuropathy pain intensity (mean= −0.29%, p=0.004), glucose intake (mean=−20.67%, p=0.025), and LDL level (mean=−7.2%, p= 0.042), There was a significant reduction in triglyceride values (mean= −4.45%, P=0.06). Total met hours activities were also increase by 0.65%. Conclusion Physical activity was associated with a decrease in A1C levels as well as a decrease in pain intensity and neuropathy symptoms. After the intervention, the glucose levels decreased and the reported neuropathy symptoms had lessened in severity according to the McGill's pain questionnaire. Physical Activity with the combination of omega 3 fatty acid pills could be associated with the decrease in neuropathy symptoms and glucose levels. Support or Funding Information This case‐only design was funded by NIH and approved by the Loma Linda University Institutional Review Board (IRB). This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,001 | 0,000 |
| Communication savante | 0,001 | 0,000 |
| Science ouverte | 0,000 | 0,001 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,002 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».