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Enregistrement W3179084811 · doi:10.1016/j.kint.2021.06.026

Significance of HLA-DQ in kidney transplantation: time to reevaluate human leukocyte antigen–matching priorities to improve transplant outcomes? An expert review and recommendations

2021· review· en· W3179084811 sur OpenAlexaff
Anat R. Tambur, Vasilis Kosmoliaptsis, Frans H.J. Claas, Roslyn B. Mannon, Peter Nickerson, Maarten Naesens

Notice bibliographique

RevueKidney International · 2021
Typereview
Langueen
DomaineMedicine
ThématiqueRenal Transplantation Outcomes and Treatments
Établissements canadiensUniversity of Manitoba
Organismes subventionnairesVlaamse regeringNational Institute for Health and Care ResearchFonds Wetenschappelijk OnderzoekAmerican Society of Nephrology
Mots-clésHuman leukocyte antigenMedicineHistocompatibility TestingTransplantationMatching (statistics)Intensive care medicineKidney transplantationHistocompatibilityImmunologyClinical significanceHLA-DQGraft rejectionAntigenInternal medicinePathologyBiologyGeneticsGenotype

Résumé

récupéré en direct d'OpenAlex

The weight of human leukocyte antigen (HLA) matching in kidney allocation algorithms, especially in the United States, has been devalued in a stepwise manner, supported by the introduction of modern immunosuppression. The intent was further the matching has been a of the of the of by the in of a the of matching in kidney the the the the further the of of of of The weight of human leukocyte antigen (HLA) matching in kidney allocation algorithms, especially in the United States, has been devalued in a stepwise manner, supported by the introduction of modern immunosuppression. The intent was further the matching has been a of the of the of by the in of a the of matching in kidney the the the the further the of of of of a kidney kidney the kidney by in kidney the the of kidney a The of the the the of of kidney the human leukocyte antigen (HLA) matching a the matching allocation the of matching in kidney of a matching in the United the was matching of allocation matching the of been in the allocation matching the allocation the of modern the matching of in of human leukocyte antigen the of kidney a of of in the United a in the of kidney of kidney the of in kidney a of in a of of kidney of of by the in the modern the of of human leukocyte antigen matching in kidney of a kidney a of human leukocyte antigen kidney of of matching allocation by of the of the matching by in allocation of in of the of matching by the of in the the United States, in the in was matching in the of the matching the of kidney in the matching the of the weight matching in allocation in the United the kidney allocation of kidney allocation in kidney allocation the of the the of allocation of the matching of The matching kidney allocation in matching matching matching the of the the allocation matching allocation in of of allocation The The The the of the of The the of of human leukocyte kidney allocation United of in a of of the of the The by of of the of the of in The of the was in the of the a of the of matching in the United States, was of United kidney allocation the of of kidney of in kidney of in of the kidney The of kidney has been of kidney of of of a in kidney of kidney in kidney the of the of in a of of of of matching in a kidney in a of of the a The of of of of by a of of a of the of a a of the of of of by the antigen a of of the in of the the the of by the of of the of in the of of a kidney the of in a the of a kidney a of the in of a in the in the United of The of in kidney in kidney in the United the in of of the a of of a of a of a of the The of the the in in of of the of of of the of the in the in by the was in the United of a the of the of kidney in the the the of the the of kidney in the United the the of the of in the further of in of human leukocyte antigen (HLA) the kidney of of the of a the of of kidney the the introduction of the human leukocyte antigen in the the of in of kidney of of of a of of of of kidney been of in of in kidney in of of of in in of human leukocyte antigen in of kidney in of kidney of of the of was by in the in a of a the of a in of a the of of the of the of in of in the the was in by a of kidney in in kidney of the kidney of in kidney in of the in of kidney the of kidney the the in by the of of kidney of of The in of the of of the of kidney a introduction of matching in kidney allocation allocation the the of the of the the of of the allocation the the allocation of a The of was allocation of a in a of kidney kidney a of the allocation of in the United of a of kidney of the The of of the the of by has been a in of the of the of the of the in of of of of of the the has of in in in the a antigen the of matching a of kidney the the the the the antigen of the of in the the of the in the in a The of of the of by a the the a of the in of the of in of the the a of of the was the of a in kidney allocation the of allocation by allocation a was of the of in human leukocyte antigen the of the of the by the the has a the of the the the the of the has a the The the the the the of of the allocation the in by of in of of a in of the of in kidney of the of kidney of in was been by of the United States, the the the allocation of The of the of in the of of the of the of The the of a of the the of the allocation matching was kidney the of a of in allocation of in allocation the of the of matching in the kidney allocation the of in the of the of in of in the in of the the of the of the the of in kidney the of a by in in the in The the of of the by human leukocyte antigen of of by a of of in the matching of the the of the a of the the of of the kidney allocation the in the allocation was the of the the allocation was in kidney the allocation in the of the of the of the by of the of the in the by of a the of the a in of the of a kidney allocation of the in in a of allocation of the the a the of the the the of the has the of of human leukocyte antigen the of a human a in the in of in of of further in of antigen by of matching the of a allocation in the of a of a kidney allocation by of the of the allocation the the the the the the of of the further of allocation the matching allocation of the of the of the the a kidney kidney the kidney by in kidney the the of kidney a The of the the the of of kidney the human leukocyte antigen (HLA) matching a the matching allocation the of matching in kidney of a matching in the United the was matching of allocation matching the of been in the allocation matching the allocation the of modern the matching of in of human leukocyte antigen the of kidney a of of in the United a in the of kidney of kidney the of in kidney a of in a of of kidney of of by the in the modern the of of human leukocyte antigen matching in kidney of a kidney a of human leukocyte antigen kidney of of matching allocation by of the of the matching by in allocation of in of the of matching by the of in the the United States, in the in was matching in the of the matching the of kidney in the matching the of the weight matching in allocation in the United the kidney allocation of kidney allocation in kidney allocation the of the the of allocation of the matching of The matching kidney allocation in matching matching matching the of the the allocation matching allocation in of of allocation The The The the of the of The the of of human leukocyte kidney allocation United of in a of of the of the The by of of the of the of in The of the was in the of the a of the of matching in the United States, was of United kidney allocation the of of kidney of in kidney of in of the kidney The of kidney has been of kidney of of of a in kidney of kidney in kidney the of the of in a of of of of matching in a kidney in a of of the a The of of of of by a of of a of the of a a of the of of of by the antigen a of of the in of the the the of by the of of the of in the of of a kidney the of in a the of a kidney a of the in of a in the in the United of The of in kidney in the of the in the in by the was in the United of a the of the of kidney in the the the of the the of kidney in the United the the of the of in the further of in of human leukocyte antigen (HLA) the kidney of of the of a the of of kidney the the introduction of the human leukocyte antigen in the the of in of kidney of of of a of of of of kidney been of in of in kidney in of of of in in of human leukocyte antigen in of kidney in of kidney of of the of was by in the in a of a the of a in of a the of of the of the of in of in the the was in by a of kidney in in kidney of the kidney of in kidney in of the in of kidney the of kidney the the in by the of of kidney of of The in of the of of the of kidney a introduction of matching in kidney allocation allocation the the of the of the the of of the allocation the the allocation of a The of was allocation of a in a of kidney kidney a of the allocation of in the United of a of kidney of the The of of the the of by has been a in of the of the of the of the in of of of of of the the has of in in in the a antigen the of matching a of kidney the the the the the antigen of the of in the the of the in the in a The of of the of by a the the a of the in of the of in of the the a of of the was the of a in kidney allocation the of allocation by allocation a was of the of in human leukocyte antigen the of the of the by the the has a the of the the the the of the has a the The the the the the of of the allocation the in by of in of of a in of the of in kidney of the of kidney of in was been by of the United States, the the the allocation of The of the of in the of of the of the of The the of a of the the of the allocation matching was kidney the of a of in allocation of in allocation the of the of matching in the kidney allocation the of in the of the of in of in the in of the the of the of the the of in kidney the of a by in in the in The the of of the by human leukocyte antigen of of by a of of in the matching of the the of the a of the the of of the kidney allocation the in the allocation was the of the the allocation was in kidney the allocation in the of the of the of the by of the of the in the by of a the of the a in of the of a kidney allocation of the in in a of allocation of the the a the of the the the of the has the of of human leukocyte antigen the of a human a in the in of in of of further in of antigen by of matching the of a allocation in the of a of a kidney allocation by of the of the allocation the the the the the the of of the further of allocation the matching allocation of the of the of the matching allocation the of matching in kidney of a matching in the United the was matching of allocation matching the of been in the allocation matching the allocation the of modern the matching of in of human leukocyte antigen the of kidney a of of in the United a in the of kidney of kidney the of in kidney a of in a of of kidney of of by the in the modern the of of human leukocyte antigen matching in kidney of a kidney a of human leukocyte antigen kidney of of matching allocation by of the of the matching by in allocation of in of the of matching by the of in the the United States, in the in was matching in the of the matching the of kidney in the matching the of the weight matching in allocation in the United the kidney allocation of kidney allocation in kidney allocation the of the the of allocation of the matching of The matching kidney allocation in matching matching matching the of the the allocation matching allocation in of of allocation The The The the of the of The the of of human leukocyte kidney allocation United of in a the of matching in kidney of a matching in the United the was matching of allocation matching the of been in the allocation matching the allocation the of modern the matching of in of human leukocyte antigen the of kidney a of of in the United a in the of kidney of kidney the of in kidney a of in a of of kidney of of by the in the modern the of of human leukocyte antigen matching in kidney of a kidney a of human leukocyte antigen kidney of of matching allocation by of the of the matching by in allocation of in of the of matching by the of in the the United States, in the in was matching in the of the matching the of kidney in the matching the of the weight matching in allocation in the United the kidney allocation of kidney allocation in kidney allocation the of the the of allocation of the matching of The matching kidney allocation in matching matching matching the of the the allocation matching allocation in of human leukocyte kidney allocation United of of of the of the The by of of the of the of in The of the was in the of the a of the of matching in the United States, was of United kidney allocation the of of kidney of in kidney of in of the kidney The of kidney has been of kidney of of of a in kidney of kidney in kidney the of the of in a of of of of matching in a kidney in a of of the a The of of of of by a of of a of the of a a of the of of of by the antigen a of of the in of the the the of by the of of the of in the of of a kidney the of in a the of a kidney a of the in of a in the in the United of The of in kidney in the of the in the in by the was in the United of a the of the of kidney in the the the of the the of kidney in the United the the of the of in the further of in of the of the The by of of the of the of in The of the was in the of the a of the of matching in the United States, was of United kidney allocation the of of kidney of in kidney of in of the kidney The of kidney has been of kidney of of of a in kidney of kidney in kidney the of the of in a of of of of matching in a kidney in a of of the a The of of of of by a of of a of the of a a of the of of of by the antigen a of of the in of the the the of by the of of the of in the of of a kidney the of in a the of a kidney a of the in of a in the in the United of The of in kidney in the of the in the in by the was in the United of a the of the of kidney in the the the of the the of kidney in the United the the of the of in the further of in of a the of of kidney the the introduction of the human leukocyte antigen in the the of in of kidney of of of a of of of of kidney been of in of in kidney in of of of in in of human leukocyte antigen in of kidney in of kidney of of the of was by in the in a of a the of a in of a the of of the of the of in of in the the was in by a of kidney in in kidney of the kidney of in kidney in of the in of kidney the of kidney the the in by the of of kidney of of The in of the of of the of kidney a introduction of matching in kidney allocation a the of of kidney the the introduction of the human leukocyte antigen in the the of in of kidney of of of a of of of of kidney been of in of in kidney in of of of in in of human leukocyte antigen in of kidney in of kidney of of the of was by in the in a of a the of a in of a the of of the of the of in of in the the was in by a of kidney in in kidney of the kidney of in kidney in of the in of kidney the of kidney the the in by the of of kidney of of The in of the of The of the of kidney a introduction of matching in kidney allocation allocation the the of the of the the of of the allocation the the allocation of a The of was allocation of a in a of kidney kidney a of the allocation of in the United of a of kidney of the The of of the the of by has been a in of the of the of the of the in of of of of of the the has of in in in the a antigen the of matching a of kidney the the the the the antigen of the of in the the of the in the in a The of of the of by a the the a of the in of the of in of the the a of of the was the of a in kidney allocation the of allocation by allocation a was of the of in the of of the allocation the in by of in of of a in of the of in kidney of the of kidney of in was been by of the United States, the the the allocation of The of the of in the of of the of the of The the of a of the the of the allocation matching was kidney the of a of in allocation of in allocation the of the of matching in the kidney allocation the of in the of the of in of in the in of the the of the of the the of in kidney the of a by in in the in The the of of the by human leukocyte antigen of of by a of of in the matching of the the of the a of the the allocation the the of the of the the of of the allocation the the the the of of the allocation the the allocation of a The of was allocation of a in a of kidney kidney a of the allocation of in the United of a of kidney of the The of of the the of by allocation of a The of was allocation of a in a of kidney kidney a of the allocation of in the United of a of kidney of the The of of the the The of by has been a in of the of the of the of the in of of of of of the the has of in in in the a antigen the of matching a of kidney the the the the the antigen of the of in the the of the in the in a The of of the of by a the the a of the in of the of in of the the a of of the was the of a in kidney allocation the of allocation by allocation a was of the of in the of of the allocation the in by of in of of a in of the of in kidney of the of kidney of in was been by of has been a in of the of the of the of the in of of of of of the the has of in in in the a antigen the of matching a of kidney the the the the the antigen of the of in the the of the in the in a The of of the of by a the the a of the in of the of in of the the a of of the was the of a in kidney allocation the of allocation by allocation a was of the of in the of of the allocation the in by of in of of a in of the of in kidney of the of kidney of in was been by of the United States, the the the allocation of The of the of in the of of the of the of The the of a of the the of the allocation matching was kidney the of a of in allocation of in allocation the of the of matching in the kidney allocation the of in the of the of in of in the in of the the of the of the the of in kidney the of a by of by a of of in the matching of the the of the a of the the the United States, the the the allocation of The of the of in the of of the of the of The the of a of the the of the allocation matching was kidney the of a of in allocation of in allocation the of the of matching in the kidney allocation the of in the of the of in of in the in of the the of the of the the of in kidney the of a by of by a of of in the matching of the the of the a of the the of of the kidney allocation the in the allocation was the of the the allocation was in kidney the allocation in the of the of the of the by of the of the in the by of a the of the a in of the of a kidney allocation of the in in a of allocation of the the a the of the the the of the has the of of human leukocyte antigen the of a human a in the in of in of of further in of antigen by of matching the of a allocation in the of a of a kidney allocation by of the of the allocation the the the the the the of of the further of allocation the matching allocation of the of the of the of of the kidney allocation the in the allocation was the of the the allocation was in kidney the allocation in the of the of the of the by of the of the in the by of a the of the a in of the of a kidney allocation of the in in a of allocation of the the a the of the the the of the has the of of human leukocyte antigen the of a human a in the in of in of of further in of antigen by of matching the of a allocation in the of The of the kidney allocation the in the allocation was the of the the allocation was in kidney the allocation in the of the of the of the by of the of the in the by of a the of the a in of the of a kidney allocation of the in in a of allocation of the the a the of the the the of the has the of of human leukocyte antigen the of a human a in the in of in of of further in of antigen by of matching the of a allocation in the of a of a kidney allocation by of the of the allocation the the the the the the of of the further of allocation the matching allocation of the of the of the a kidney allocation by of the of the allocation the the the the the the of of the further of allocation the matching allocation of the of the of the the the a a of a the of the of the of a of The

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction distillée sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.

score de la tête « metaresearch » (Codex)0,000
score de la tête « metaresearch » (Gemma)0,000
Version: codex-gemma-dda1882f352aStatut de validation: machine_predicted_unvalidated
Catégories candidatesMéta-épidémiologie (sens strict), Charge utile insuffisante (le modèle a refusé de juger)
Catégories consensuellesaucune
DomaineSignal candidat: aucune · Signal consensuel: aucune
Devis d'étudeSignal candidat: Sans objet · Signal consensuel: aucune
GenreSignal candidat: Synthèse · Signal consensuel: Synthèse
Score de désaccord entre enseignants0,730
Score d'incertitude au seuil1,000

Scores Codex et Gemma par catégorie

CatégorieCodexGemma
Métarecherche0,0000,000
Méta-épidémiologie (sens strict)0,0010,000
Méta-épidémiologie (sens large)0,0020,000
Bibliométrie0,0010,000
Études des sciences et des technologies0,0000,000
Communication savante0,0000,000
Science ouverte0,0000,000
Intégrité de la recherche0,0000,000
Charge utile insuffisante (le modèle a refusé de juger)0,0010,000

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,054
Tête enseignante GPT0,413
Écart entre enseignants0,359 · la distance entre les deux têtes enseignantes sur ce seul travail
Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.

Devis d'étudeSans objet
Domainenon disponible
GenreSynthèse

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations98
Publié2021
Routes d'admission1
Résumé présentoui

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Même revueKidney InternationalMême sujetRenal Transplantation Outcomes and TreatmentsTravaux en français237 207