Clinical Effect and Adverse Reactions of Modified Electroconvulsive Therapy for Refractory Obsessive-Compulsive Disorder
Notice bibliographique
Résumé
To explore the clinical effect and adverse reactions of modified electroconvulsive therapy for refractory obsessive-compulsive disorder. 76 patients with refractory obsessive-compulsive disorder admitted to our hospital from June 2019 to February 2021 were selected and randomly divide into two groups, with 38 cases in each group. The control group was treated with conventional drug treatment and the study group was treated with modified electroconvulsive therapy on the basis of the control group. Follow-up was given every 6 w for a total of 12 w and corresponding evaluation was given every follow-up. The total effective rate of the study group was 92.11 %, which was significantly higher than that of the control group (78.95 %) and the difference was statistically significant (p<0.05). There was no significant difference in Yale-brown obsessive compulsive scale, Hamilton anxiety scale, Hamilton depression scale, Montreal cognitive assessment scale and Tang danlin scores between the two groups before treatment (p>0.05). At the 6th and 12th w after treatment, it increased with time compared with that before treatment, The scores of Yale-brown obsessive compulsive scale, Hamilton depression scale and Hamilton anxiety scale decreased gradually. The difference was statistically significant (p<0.05). The scores of Yale-brown obsessive compulsive scale, Hamilton anxiety scale and Hamilton depression scale in the study group were significantly lower than those in the control group at the 6th and 12th w. The difference was statistically significant (p<0.05), while the Montreal cognitive assessment scale scores and Tang danlin scores of patients in the study group were significantly higher than those in the control group at the 6th and 12th w after treatment than before treatment and the difference was statistically significant (p<0.05). The incidence of near memory impairment in the study group was significantly higher than that in the control group (p<0.05), but there was no significant difference in adverse reactions such as agitation, blurred vision, constipation and abnormal examination items (p>0.05). Modified electroconvulsive therapy for refractory obsessive-compulsive disorder has good clinical effect, low adverse reactions and can effectively improve patient’s anxiety, depression and obsessive-compulsive symptoms, and improve patient’s quality of life and cognitive function. However, there is a high incidence of near memory impairment.
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Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,001 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».