Glossary

Glossaryakinesia Complete lack of movement.aluminum The 13th element in the periodic table.Aluminum is the third most common element in the earth's crust after oxygen and silicon, and the most common metal.In nature, it is mostly complexed with silicate compounds.The aluminum ion (Al +3 ) is a cellular toxin and, in particular, a neurotoxin.Aluminum compounds find widespread use in a range of industrial and medical applications.Aluminum has been linked epidemiologically and experimentally to neurological diseases/disorders of various kinds.Alzheimer's disease A disease involving the loss of neurons in the brain, primarily in the cortex and hippocampus, which are concerned with learning and memory.Hallmark pathological features, seen post mortem, are the presence of amyloid beta (Aβ) protein plaques and neurofibrillary tangles (NFTs).Alzheimer's disease is progressive and is the most common of the age-related neurological diseases.Treatment options are limited in effectiveness, although newer therapies offer some potential promise.amyloid beta (A𝛃) A protein deposit associated with neuron degeneration.Amyloid is found in the brains of individuals with Alzheimer's disease in the form of dense insoluble protein blobs called "plaques."amyloid precursor protein (APP) A protein found in various organs, including the brain, heart, kidneys, lungs, spleen, and intestines.The normal function of APP in the body is unknown.In Alzheimer's disease, APP is abnormally processed and converted to amyloid beta (Aβ) protein -the protein deposited in amyloid plaques.amyotrophic lateral sclerosis-parkinsonism dementia complex (ALS-PDC) The neurological disease spectrum of Guam and other locations in the Western Pacific.ALS-PDC describes diseases that range from ALS to a form of parkinsonism with dementia, as well as a combination of the two.There is also a form of Alzheimer's-like disease.ALS-PDC has been linked epidemiologically to the consumption and other uses of the seeds of the cycad (C.micronesica K. D. Hill).amyotropic lateral sclerosis (ALS) Also known as Lou Gehrig's disease.One of the motor neuron diseases that destroy lower and/or upper motor neurons.It is typically fatal within 3-5 years from clinical diagnosis.Signs include the progressive loss of motor functions leading to respiratory failure.There are both sporadic and familial forms, the former making up the vast majority of all cases.A loss of cognitive function may also occur.There are currently no viable treatment options.antibody A type of immunoglobulin (Ig): a large Y-shaped protein produced by plasma cells.Igs come in a variety of isotypes, classified based on the type of heavy

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.