S34 Evolving Trends and Concentrations in Inflammatory Bowel Disease Research 2000-2020
Notice bibliographique
Résumé
Background: Inflammatory bowel disease (IBD) is a chronic inflammatory disease with complex pathophysiology and treatment. There has been an accelerating rise in both incidence and prevalence since the second half of the 20th century. Addressing this increasing burden requires a strong evidence base on IBD diagnosis, management, natural history and complications. The objective of this study is to assess the status of IBD research worldwide and highlight potential gap areas. Methods: We searched the Web of Science core collection database for peer-reviewed publications related to IBD. Search results were limited to the period between years 2000 and 2020. The publications were divided by the country of affiliation of the corresponding author, funding status and research topics. The number of publications was normalized to the IBD national prevalence and incidence for each country using data from Institute for Health Metrics and Evaluation. Additionally, the articles were categorized into research topics via the use of predetermined terms based on title, key-terms and abstract words; these categories are not mutually exclusive, for example a publication comparing medical therapy to surgery will be present in both categories. Results: A total of 25,640 articles were retrieved from the search. Trends show a steady rise in the number of publications with an almost 5 times increase from 2000 to 2020. Subdivision of the timelines by countries shows the highest rise for China and the USA. 88% of the publications originated from just 20 countries with USA, China, and Japan being the top 3. The collaboration for these twenty most prolific countries with other countries was limited to only 19% of the articles originating from a multinational collaboration, with Canada (33%), Belgium (30%) and Sweden (29%) having the most collaborations. When standardizing the number of publications by the IBD incidence and prevalence, the most prolific countries respectively would be China, USA, and India. The most common research topics included FDA-approved medications (n = 4526, 17.7%), oncology in IBD (n = 3622, 14.1%) and surgery (n = 3074, 12.0%). In contrast, there were fewer studies of quality of life (n = 864, 3.4%), microbiome (n = 786, 3.1%), health maintenance (n = 692, 2.7%) and epidemiology (n=452, 1.8%). Furthermore, a differential in the funding distribution exists among the topics with 14.9% of the funded articles addressing FDA-approved medications and 12.5% for genetics while less for quality of life (3.2%), epidemiology (2.1%) and health maintenance (2.0%). Conclusion(s): Despite an immense rise in the number of IBD related publications from 2000 to 2020, discrepancies do exist in the distribution of publications across the globe and across the research topics. Several clinically unmet needs for IBD patients were reflected in the discrepancies in the research topics.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».