Development and implementation of a concept for substitution of the highly hazardous substances with safe chemical alternatives
Notice bibliographique
Résumé
Introduction. The concept of chemical substitution is now increasingly included in policy and regulatory efforts around the world to reduce the risks of chemicals to human health and the environment, as well as in industry initiatives for the sustainable management of chemicals. With the exception of conventional substances regulated by EEC documents, unfortunately, there is no legislatively established mechanism for identifying, banning and limiting the production and consumption of highly hazardous chemical compounds in the Russian Federation. The purpose of the research is to develop and scientifically substantiate the concept of replacing highly hazardous chemicals with safer alternatives. Materials and methods. The guidelines and recommendations of the OECD, WHO, ILO, FAO, UNEP, as well as regulatory and methodological documents of the EU, the USA, Canada and other states on the criteria for classifying substances as highly hazardous, organizing and monitoring them in environmental objects and selection of safe chemical alternatives were studied and analyzed. Results. The concept of substitution includes the scientific substantiation of the criteria for classifying substances as highly hazardous, the organization and generalization of data from monitoring the human environment and the circulation of hazardous chemical products on the market, the development of a list of highly hazardous chemicals that are priority for regulation; selection of safe alternatives and their comparative analysis, taking into account the assessment of the advantages of the alternative over the existing technology/substance, implementation of management decisions. The criteria for identifying substances of highly concern and selecting their alternatives are the following indicators: biological activity (carcinogens, mutagens, reprotoxicants class 1A and 1B in accordance with GHS, endocrine disruptors); stability in the environment; bioaccumulative potential; the possibility of cross-media transfer; aquatic toxicity (acute and chronic toxicity of hazard class 1 in accordance with GHS); production volumes (volumes of emissions and discharges); number of contacts. Conclusion. The analysis of the international practice of regulating highly hazardous chemicals indicates the need to implement at the national level and within the framework of the Eurasian Economic Union a program for the systematic monitoring of high-risk chemicals circulating on the market in order to withdraw them from circulation and replace them with safe analogues. Implementation of the concept of replacing highly hazardous substances with safe chemical alternatives allows to create a draft national list of banned and restricted highly hazardous chemicals relevant to various industries (food, materials, basic chemistry).
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».