Study identifies prostate cancer-related disparities between Indigenous and non-Indigenous men in a universal health care system
Notice bibliographique
Résumé
The Cochrane Library.The single most reliable source of evidence in healthcareThe Cochrane Reviews highlighted below are available from the Cochrane Database of Systematic Reviews (www.thecochranelibrary.com) Cochrane Reviews are regularly updated as new evidence emerges and in response to feedback, and the Cochrane Database of Systematic Reviews should always be consulted for the most recent version of the review. Study identifies prostate cancer-related disparities between Indigenous and non-Indigenous men in a universal health care system JULY 10, 2023 -Indigenous people in Canada have higher illness rates and lower life expectancies than non-Indigenous Canadians.A new study reveals that Indigenous men in the country who have prostate cancer are being diagnosed with more advanced and more aggressive tumors than their non-Indigenous counterparts.The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.To identify disparities in prostate cancer screening, diagnoses, management, and outcomes between Indigenous and non-Indigenous men in Canada, a team led by Adam Kinnaird, MD, PhD, of the University of Alberta, examined data on 1,444,974 men who were screened for prostate cancer in 2014-2022 and were enrolled in the Alberta Prostate Cancer Research Initiative.When they examined testing rates by postal code, the investigators found that men in Indigenous communities were less likely to have prostate-specific antigen (PSA) tests to detect prostate cancer than men outside of Indigenous communities (32 vs. 46 PSA tests per 100 men aged 50-70 years within one year).Also, among 6,049 men diagnosed with prostate cancer, Indigenous men were more likely to have PSA levels 10 ng/mL (48% vs. 30%), stage II or higher cancer (65% vs. 47%), and high-grade tumors (79% vs. 64%) than non-Indigenous men.In addition, over a median follow-up of 3.3 years, Indigenous patients were 2.3-times more likely to experience cancer spread, or metastasis, than non-Indigenous patients."What is critical about this is that these results come from within a publicly funded universal health care system in which all peoples should have equal access to care," said Dr. Kinnaird."The findings are significant because they identify Indigenous men as a population at risk for more aggressive prostate cancer and potentially worse survival.Key infrastructure changes, including better access to primary care physicians, may help improve prostate cancer screening and identify men at earlier, and curable, stages of the disease.
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Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,002 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,001 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».