S1167 Communicating Needs and Features of IBD Experiences (CONFIDE) Survey: Prevalence and Experiences of Bowel Urgency–Comparison Between Male and Female Patients With Moderate-to-Severe Ulcerative Colitis
Notice bibliographique
Résumé
Introduction: Here, we used data from the Communicating Needs and Features of IBD Experiences (CONFIDE) survey to compare the prevalence and experiences of bowel urgency (BU) between male and female patients in the US and Europe (EU). Methods: An online, quantitative, cross-sectional survey was conducted among patients with moderate-to-severe UC in the US and EU5 (France, Germany, Italy, Spain, and UK). Data included patient perspectives on experience, impact, and burden of UC-related symptoms. The distribution of continuous and categorical data was compared between male and female patients using t-test and chi-square test, respectively. A P-value of < 0.05 was deemed significant, and no multiplicity adjustment was considered. Results: 200 patients (male=123, female=77) completed the survey in the US and 556 (male=319, female=236, one patient “preferred not to say”) in the EU5. A higher proportion of males were receiving advanced therapy (65% vs. 35%). The top three symptoms experienced by male and female patients in the past month were diarrhoea (51% and 57%), BU (33% and 37%), and increased stool frequency (35% and 28%). Among the patients who had ever experienced BU, 76% male and 71% female patients reported experiencing BU at least once a week in the past 3 months. Also, 39% male and 40% female patients reported wearing a diaper/pad/other protection at least once a week in the past 3 months due to fear/anticipation of BU-related accidents. The mean Urgency Numeric Rating Scale scores (0=no urgency, 10=worst possible urgency) over the last 3 days were high among both male (7.8) and female (8.0) patients. Approximately 50% of both male and female patients reported that they needed to visit the bathroom within 5-15 min due to BU, and 2% male and 4% female patients reported not being able to make it to the bathroom in time. Both male and female patients ranked BU and BU-related accidents among the top five most impactful symptoms and reported that BU considerably impacted their daily activities. Most patients with an experience of BU reported that it negatively affected their work or school (male=80%, female=74%). Conclusion: Bowel urgency was among the top three symptoms most frequently reported by both male and female patients with moderate-to-severe UC. The experiences and impacts of bowel urgency were largely similar between sexes and considerably affected work and daily activities of patients, irrespective of their sex.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,003 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,001 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,001 | 0,000 |
| Science ouverte | 0,000 | 0,001 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,004 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».