S1167 Communicating Needs and Features of IBD Experiences (CONFIDE) Survey: Prevalence and Experiences of Bowel Urgency–Comparison Between Male and Female Patients With Moderate-to-Severe Ulcerative Colitis
Bibliographic record
Abstract
Introduction: Here, we used data from the Communicating Needs and Features of IBD Experiences (CONFIDE) survey to compare the prevalence and experiences of bowel urgency (BU) between male and female patients in the US and Europe (EU). Methods: An online, quantitative, cross-sectional survey was conducted among patients with moderate-to-severe UC in the US and EU5 (France, Germany, Italy, Spain, and UK). Data included patient perspectives on experience, impact, and burden of UC-related symptoms. The distribution of continuous and categorical data was compared between male and female patients using t-test and chi-square test, respectively. A P-value of < 0.05 was deemed significant, and no multiplicity adjustment was considered. Results: 200 patients (male=123, female=77) completed the survey in the US and 556 (male=319, female=236, one patient “preferred not to say”) in the EU5. A higher proportion of males were receiving advanced therapy (65% vs. 35%). The top three symptoms experienced by male and female patients in the past month were diarrhoea (51% and 57%), BU (33% and 37%), and increased stool frequency (35% and 28%). Among the patients who had ever experienced BU, 76% male and 71% female patients reported experiencing BU at least once a week in the past 3 months. Also, 39% male and 40% female patients reported wearing a diaper/pad/other protection at least once a week in the past 3 months due to fear/anticipation of BU-related accidents. The mean Urgency Numeric Rating Scale scores (0=no urgency, 10=worst possible urgency) over the last 3 days were high among both male (7.8) and female (8.0) patients. Approximately 50% of both male and female patients reported that they needed to visit the bathroom within 5-15 min due to BU, and 2% male and 4% female patients reported not being able to make it to the bathroom in time. Both male and female patients ranked BU and BU-related accidents among the top five most impactful symptoms and reported that BU considerably impacted their daily activities. Most patients with an experience of BU reported that it negatively affected their work or school (male=80%, female=74%). Conclusion: Bowel urgency was among the top three symptoms most frequently reported by both male and female patients with moderate-to-severe UC. The experiences and impacts of bowel urgency were largely similar between sexes and considerably affected work and daily activities of patients, irrespective of their sex.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.004 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".