Specialist Program in Pathobiology: An undergraduate program in mechanisms of disease
Notice bibliographique
Résumé
A specialist undergraduate program was developed in Pathobiology at the University of Toronto in order to teach current concepts in mechanisms of disease to students selected from a large undergraduate life science student population in the Faculty of Arts and Science. The goal of the program was not to train laboratory professionals or to be a pre‐med course. New faculty appointments supported by the university provost, Faculty of Medicine and department were required. The faculty of the Department of Laboratory Medicine and Pathobiology was expanded to include a faculty of both basic and clinical scientists who were able to teach a unique curriculum consisting of one full and ten half courses on diverse topics in pathobiology, including cardiovascular pathobiology, neurodegenerative disease, cancer, inflammation, and immunopathology. Following foundation courses in the various life sciences in second year of the Arts and Science curriculum, the Pathobiology courses are introduced in third and fourth year. The courses are small with no more than 30 students in a class which permits more discussion and opportunities for mentoring of students. Students are given didactic lectures and prepare reports and grant applications focused on topics in pathobiology. Reading the current literature on pathogenesis of disease is required. There are hands‐on research opportunities through project course work and twelve‐week summer student placements in graduate faculty research laboratories where students are supervised by faculty, interact with graduate students and carry out a project which they report upon in poster format. Many students utilized these opportunities to select labs for graduate studies. Fourteen classes of Hons. B.Sc. students have graduated from the program. Outcomes were tracked for students graduating between 2007 and 2012 and outcomes for 99 students (70% of available graduates) were determined for the year following graduation. Of these, 52 went to medical school (including three into MD/PhD programs), 31 to graduate life sciences research, 10 to other health care‐related pursuits (e.g., pharmacy, public health), and six to other non‐medical careers. Two former students are currently residents in anatomic pathology. The undergraduate specialist (honours) program in Pathobiology requires a dedicated research faculty who are able to teach at the intersection of basic pathobiology and clinical disease and provides students with an excellent background and preparation for careers in basic discovery and clinical biomedical research.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,004 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,002 | 0,001 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,002 | 0,001 |
| Études des sciences et des technologies | 0,003 | 0,001 |
| Communication savante | 0,003 | 0,001 |
| Science ouverte | 0,002 | 0,006 |
| Intégrité de la recherche | 0,002 | 0,003 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,039 | 0,016 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».