O41 Epidemiological analysis and overall survival of gastric cancer in a developing middle eastern country over 18 years
Notice bibliographique
Résumé
Introduction Gastric malignancies result in significant burden due to the resultant morbidity and mortality. Identifying the epidemiology of gastric cancer in the Middle East, including the incidence and overall survival, are of prominent importance in the policy advocacy, long-term management planning and treatment as it provides adequate risk stratification that is vital in resource limited countries. Methods 3518 individuals residing in Jordan who were diagnosed with gastric cancer during the period 2000–2018 were included in the study after retrieval of data from the official registry of cancer studies in Jordan, the Jordan Cancer Registry. Epidemiological statistical analysis was performed to establish the epidemiological characteristics of gastric cancer in Jordan. Results 3518 individuals with a mean age of 58.3 ± 13.9 years old were included. A male predominance of 61.7% was noted. The vast majority of the participants (84.9%) were reported to be non-smokers at the time of diagnosis. The most prevalent tumour location was the gastric antrum as found in 71.8% of the patients followed by the gastric cardia which was reported in 11.5% of the patients. Worrisomely, 42.2% of the patients had poorly differentiated tumours at the time of diagnosis while only 4.07% of patients had well differentiated tumours. At the time of diagnosis, distant metastasis was identified in a concerning portion of patients (23.5%). In contrast, 11.4% of the patients were found to have localized disease. Among the regional spread subcategories, inclusion of both direct extension and lymph node was the most prevalent as reported in 39.7% of the patients. In regard to the morphology, unspecified adenocarcinoma was the most prevalent gastric malignancy morphology (52%), followed by signet ring cell carcinoma that was identified in 20.2% of the patients. The overall survival was 81.6%, 71.0%, 64.1%, 48.2%, and 38.6% at 1-year, 2-year, 3-year, 4-year, and 5-year interval, respectively. A statistically insignificant increase of 0.6% in the crude incidence of gastric malignancies over 18 years was identified. Conclusion Gastric cancer in Jordan demonstrated a drastic variation in comparison to the internationally reported trends in regard to the overall survival and most commonly involved gastric sites. Of particular importance and significance is the overall 5-year survival rate of gastric cancer in Jordan which mandates prompt and effective intervention.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,001 | 0,002 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».