O41 Epidemiological analysis and overall survival of gastric cancer in a developing middle eastern country over 18 years
Bibliographic record
Abstract
Introduction Gastric malignancies result in significant burden due to the resultant morbidity and mortality. Identifying the epidemiology of gastric cancer in the Middle East, including the incidence and overall survival, are of prominent importance in the policy advocacy, long-term management planning and treatment as it provides adequate risk stratification that is vital in resource limited countries. Methods 3518 individuals residing in Jordan who were diagnosed with gastric cancer during the period 2000–2018 were included in the study after retrieval of data from the official registry of cancer studies in Jordan, the Jordan Cancer Registry. Epidemiological statistical analysis was performed to establish the epidemiological characteristics of gastric cancer in Jordan. Results 3518 individuals with a mean age of 58.3 ± 13.9 years old were included. A male predominance of 61.7% was noted. The vast majority of the participants (84.9%) were reported to be non-smokers at the time of diagnosis. The most prevalent tumour location was the gastric antrum as found in 71.8% of the patients followed by the gastric cardia which was reported in 11.5% of the patients. Worrisomely, 42.2% of the patients had poorly differentiated tumours at the time of diagnosis while only 4.07% of patients had well differentiated tumours. At the time of diagnosis, distant metastasis was identified in a concerning portion of patients (23.5%). In contrast, 11.4% of the patients were found to have localized disease. Among the regional spread subcategories, inclusion of both direct extension and lymph node was the most prevalent as reported in 39.7% of the patients. In regard to the morphology, unspecified adenocarcinoma was the most prevalent gastric malignancy morphology (52%), followed by signet ring cell carcinoma that was identified in 20.2% of the patients. The overall survival was 81.6%, 71.0%, 64.1%, 48.2%, and 38.6% at 1-year, 2-year, 3-year, 4-year, and 5-year interval, respectively. A statistically insignificant increase of 0.6% in the crude incidence of gastric malignancies over 18 years was identified. Conclusion Gastric cancer in Jordan demonstrated a drastic variation in comparison to the internationally reported trends in regard to the overall survival and most commonly involved gastric sites. Of particular importance and significance is the overall 5-year survival rate of gastric cancer in Jordan which mandates prompt and effective intervention.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".