P390 Epidemiological analysis and overall survival of pancreatic cancer in a developing middle eastern country over 18 years
Notice bibliographique
Résumé
Introduction Pancreatic malignancies impose paramount global health burden due to the resultant morbidity and mortality. The determination and identification of the leading epidemiological features and outcomes of pancreatic cancer in developing middle eastern countries, such as Jordan, is of prominence in risk stratification and introduction of effective therapeutic measures. Methods Comprehensive data on 1679 individuals, both males and females, of different nationalities residing in Jordan who were diagnosed with pancreatic cancer during the period of 2000–2018 was retrieved from the official cancer reporting institution in Jordan, the Jordan Cancer Registry. Statistical analysis was performed to establish the epidemiological features, including crude incidence and overall survival, of pancreatic cancer in Jordan over 18 years. Results A total of 1679 individuals with a mean age of 59.5 ± 12.1 years old and a male predominance of 62.4% were included in the analysis. 17.3% of the study population were reported to be smokers at the time of diagnosis. 26.1% of the individuals had tumour at the head of the pancreas despite that a substantial portion of the enrolled individuals (62.7%) did not have a specified tumour location. 3.7% and 3.5% of the individuals were documented to have tumour in the body of the pancreas and tail of the pancreas, respectively, while 21 individuals (1.25%) were reported to have tumour in the pancreatic duct. Despite that a staggeringly significant portion of the individuals did not have a determined tumour grade, moderately differentiated tumours were identified in 21.3% of the patients, followed by poorly differentiated tumours in 12.8% of the patients. An alarmingly significant portion of the study population (44.4%) had distant metastasis at the time of diagnosis whereas only 8.4% of the individuals had localized disease. Adenocarcinoma was the most prevalent morphology (53.6%). Intraductal carcinoma was identified in 7.9% of the patients. A statistically significant increase in the crude incidence of pancreatic cancer in Jordan over 18 years was noted with a crude incidence estimated effect of 0.059. The overall survival rate was 65.9%, 47.1%, 37.2%, and 19.6% at 1-year, 2-year, 3-year, and 5-year interval, respectively. Conclusions Pancreatic cancer in Jordan has witnessed a worrisome and significant incline in incidence with a staggeringly poor overall survival mandating prompt recognition and further investigation.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,001 | 0,002 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,002 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».