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Enregistrement W53234381

Ethics of Stem-Cell Research: A Framework for Ethical Dialogue regarding Sources of Conflict

2007· article· en· W53234381 sur OpenAlexaboutno aff
Francis C. Dane, James V. Finkbeiner

Notice bibliographique

RevueForum on public policy · 2007
Typearticle
Langueen
DomaineMedicine
ThématiqueEthics and Legal Issues in Pediatric Healthcare
Établissements canadiensnon disponible
Organismes subventionnairesnon disponible
Mots-clésEthical dilemmaValue (mathematics)Environmental ethicsPolitical scienceSociologyEpistemologyLawPhilosophy
DOInon disponible

Résumé

récupéré en direct d'OpenAlex

Introduction One need hardly point out that Darwin's (1859) Origin produced controversy from its first appearance. Equally obvious is fact that, however much value scientists place on evolutionary theory as an explanatory mechanism, theory remains controversial outside of scientific circles and within nearly every venue in which scientific circles overlap with other areas of inquiry. The controversy exceeds even that of Galileo's (1632/1967) heliocentric viewpoint in his Dialogue, prompting Stephen Gould to claim controversy has reached point at which the very integrity of education hangs in balance (Alters and Alters 2001, p. 1). Indeed, evolution may well be only scientific theory about which scientists have felt compelled to write book to inform educators about how to deal with a war within scientific classrooms (Alters and Alters 2001, p. 14). Public attitudes about evolution, similar to those concerning abortion and capital punishment, have become polarized such that most people hold position that allows little latitude for rational consideration of informational contrary to their position (beaux, Dane, and Wrightsman 1993). The purpose of present paper is to present framework for discussing ethics of stem-cell research in hopes of preventing its joining ranks of polarized attitudes. I do not wish to imply that stem-cell research is not yet controversial. Indeed, variety of governmental positions on various types of stem-cell research provides but one indication of extent to which disagreements exist within worldwide community, and sometimes with single nation. The General Assembly of United Nations failed to reach agreement on treaty regarding somatic cell nuclear transfer, also known as SCNT (Caulfield and von Tigerstrom 2005). Caulfield and Bubela (2007) report that Ireland and Austria forbid any research involving embryos while Italy is moving toward similar ban. United Kingdom, Japan, Sweden, and South Korea, in contrast, allow virtually all types of stem-cell research, while France and Canada allow some types of stem research; SCNT was, however, recently made criminal activity in Canada. The President of United States froze embryonic stem-cell research funding, including SCNT (Bush 2001), after which California voters responded by approving $3 billion bond to fund fetal stem-cell research, including SCNT (Californians approve stem cell research funding 2004). Aramesh (2007) reports that Iran permits stem-cell research, including SCNT, and notes that Muslim scholars prohibit only research directed toward reproductive cloning. (The latter position is in line with virtually all bioethicists.) These disagreements notwithstanding, most political jurisdictions have no explicit policy regarding stem-cell research; in all jurisdictions, absence of framework for dialogue prevents many from considering rationally ethical aspects of stem-cell research. If we are to reach consensus regarding ethics of stem-cell research, we must have single framework, common language with which to discuss differences. It is important that any framework for discussing propriety of stem-cell research be presented at conceptual or principled level. Ethical discussions are not about whether or not rule or law has been broken; such are moral, legal, or administrative decisions. Instead, ethical discussions are about whether or not rule or standard is worthwhile or about which of several, incompatible rules should be given priority (e.g., Dane and Parish 2006; Schroeder 2000; Singer 2000). As has been illustrated, rules can change from one jurisdiction to another or, as noted below, from one set of religious rules to another. Principles, in contrast, tend to be more generalizable, more applicable to wider variety of situations, locations, and topics. Consider, for example, variety of religious positions regarding beginning of human life, which range from conception to an infant's first cry to as long as several years after birth (Morowitz and Trefil 1992). …

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction machine sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.

score de la tête « metaresearch » (Codex)0,043
score de la tête « metaresearch » (Gemma)0,022
Version: metacan-v3-hybrid-931329e0061cStatut de validation: machine_predicted_unvalidated
Catégories candidatesaucune
Catégories consensuellesaucune
DomaineSignal candidat: aucune · Signal consensuel: aucune
Devis d'étudeSignal candidat: Théorique ou conceptuel · Signal consensuel: Théorique ou conceptuel
GenreSignal candidat: Empirique · Signal consensuel: aucune
Score de désaccord entre enseignants0,043
Score d'incertitude au seuil0,229

Scores du classifieur distillé par catégorie (deux têtes)

CatégorieCodexGemma
Métarecherche0,0430,022
Méta-épidémiologie (sens strict)0,0010,001
Méta-épidémiologie (sens large)0,0010,001
Bibliométrie0,0040,003
Études des sciences et des technologies0,0120,086
Communication savante0,0230,018
Science ouverte0,0050,010
Intégrité de la recherche0,0230,012
Charge utile insuffisante (le modèle a refusé de juger)0,0060,001

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,246
Tête enseignante GPT0,496
Écart entre enseignants0,250 · la distance entre les deux têtes enseignantes sur ce seul travail
Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.

Les modèles n’ont appliqué aucune catégorie : rien dans la taxonomie ne correspondait à ce travail.
Devis d'étudeThéorique ou conceptuel
Domainenon disponible
GenreEmpirique

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations1
Publié2007
Routes d'admission1
Résumé présentoui

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