Notice bibliographique
Résumé
Introduction A vast amount of literature examines legal, ethical and social issues involved in collection and use of blood and other biological samples for research purposes. For example, a recent study analyzed nearly 600 papers on consent and biobank (1) Some literatuAre focuses on prospective collection of blood or other biological materials for purpose of creating biobanks as a resource for biomedical Other literature addresses secondary research use of stored samples that were initially collected for clinical purposes. In contrast with wealth of literature addressing these topics, comparatively little has been written about research use of blood that is collected by blood service agencies meet blood supply needs in health care system. Public communication intended motivate people donate blood emphasizes use of blood as a precious resource sustain and save lives. Yet, blood that is collected primarily for medical care may also be stored and used for Some recent literature underscores potential benefits of creating and using repositories of donated blood for research purposes. In an editorial in Transfusion, Allain and Busch argue we feel strongly that research repositories are key advancing field [of transfusion medicine] and should be established and maintained. (2) They also suggest that such repositories can support broader research inquiries beyond those directly related transfusion medicine, that repository samples need be made widely available scientific community and should be linked with other biobanking initiatives. (3) Other researchers discuss opportunities for using blood repositories as a resource for genetic studies. (4) Another scholar cautions, however, that broader research use of blood collected by blood banks raises questions about linking the ethic of with goal of medical research. (5)Indeed, in any efforts expand research uses of blood collected by blood service agencies, it is critically important not undermine trust that donors have in these organizations. And while Allain and Busch advocate for wide research access biorepositories of donated blood, they also acknowledge that to make these resources powerful research tools it is important address ethical and/or informed consent considerations when specimens are collected allow for their future use.... (6) This article explores issues concerning research use of blood donated blood banking organizations. It begins with an overview of practices of these organizations in retaining samples and creating biorepositories. Next, article examines donors' knowledge of and attitudes toward use of donated blood in Available research shows that donors express trust in blood banks make appropriate choices for how donated blood is used, however donors may give little thought research use and focus, instead, on use for medical care purposes. Whatever their level of awareness about research uses, donors maintain a privacy interest in retained samples. The article discusses relevant privacy aspects, then turns a discussion of consent challenges and options. Blood service organizations that wish store, use and share donated samples for research should ensure that consent for research is addressed in a manner than sustains trust relationship between blood bank and donor. The concluding section of article suggests several areas for further research inform policy options for consent research use of donated blood. Blood Service Organizations and Retention and Use of Stored Samples A survey of practices among blood service agencies in more than 15 countries found that most store samples for some period, ranging from several days indefinite storage. A distinction is noted between donation specimens retained primarily for [the blood agency's] operational purposes and collections of donor and/or recipient biospecimens that are made available research community. …
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,032 | 0,128 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,004 | 0,007 |
| Études des sciences et des technologies | 0,004 | 0,007 |
| Communication savante | 0,009 | 0,007 |
| Science ouverte | 0,002 | 0,004 |
| Intégrité de la recherche | 0,005 | 0,004 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,030 | 0,004 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».