Biochemical and hematological analytes in the assessment of energy status and risk of disease in dairy cows during the transition period
Notice bibliographique
Résumé
Biochemical and hematological analytes were used to better understand some of the pathophysiological processes involved in the transition period and contribute to the prediction of risk of disease, particularly retained placenta (RP); three studies were carried out. In the first study, based on prepartum biochemical and hematological profiles of 1038 Holstein cows, a multivariable logistic model was used to predict the risk of RP. Cholesterol and fatty acids were associated with a higher risk of RP. In the second study, blood samples from 37 Holstein cows in the week before calving and 47 cows in the week after calving were obtained at 1 hour (-1h) before and 4(4h) and 10(10h) hours after the first feed offering. Fatty acids were determined in the precalving samples and [beta]-hydroxybutyrate (BHB) in the postcalving samples. Lipoprotein electrophoresis were carried out on 3 sera of 10 randomly selected cows in each group. Thirty two percent of cows had >=0.4 mmol/L of fatty acids at -1h, compared to 16% at 4 h and 10h in the precalving cows. In the postcalving samples, the proportions of cows with >=1400 [mu]mol/L of BHB were 8.5%, 10.6%, and 12.8% respectively. The low density lipoproteins were markedly reduced in the postcalving group. Cows were twice as likely to be above the suggested cut-point for increased disease risk when they were sampled before feeding to measure fatty acids. Lipoprotein electrophoresis results were of limited utility for assessing energy status. In the third study, serum and whole blood measurements from 1078 high producing cows from 20 herds from Southern Ontario were used to determine reference values in the week prepartum and the week postpartum. Cows that presented clinical disease were excluded. In sera, BHB, fatty acids, cholesterol, urea, glucose, calcium and phosphorus were determined. In whole blood, WBC, and differential leukocytes were counted. There were significant differences between the precalving and postcalving groups for all the biochemical analytes and eosinophils. Other hematological analytes were not significantly different. The results were also different to reference ranges of mid-lactation cows. Differential reference values of transition cows are required for accurate interpretation of results.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,001 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,001 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».