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Enregistrement W7066019901

Functional and bioactive properties of protein isolates and hydrolysates from 
\ncamelina and sophia seed meals

2023· dissertation· en· W7066019901 sur OpenAlexfundno aff

Notice bibliographique

RevueMemorial University Research Repository (Memorial University) · 2023
Typedissertation
Langueen
DomaineEngineering
ThématiqueOptical Polarization and Ellipsometry
Établissements canadiensnon disponible
Organismes subventionnairesNatural Sciences and Engineering Research Council of CanadaMemorial University of Newfoundland
Mots-clésCamelinaHydrolysateCamelina sativaFunctional foodFood productsSoy proteinFood industryPlant protein
DOInon disponible

Résumé

récupéré en direct d'OpenAlex

Camelina and sophia meals, often seen as by-products from these oilseed crops, are 
\npromising resources in the battle against food waste due to their high nutrient content. 
\nThese by-products, rich in proteins, fibers, essential amino acids, and antioxidants, could 
\nbe repurposed as functional food ingredients or nutraceuticals, thus enhancing food's 
\nnutritional value. These meals align with sustainability goals, as they can decrease waste 
\nand promote a circular economy. The rising consumer interest in plant-based diets and 
\nalternative protein sources further highlights their potential as valuable food products. 
\nFurther research could position these oilseed by-products as crucial players in reducing 
\nfood waste and creating nutritious, functional, and sustainable food products.
\nThis research involved the acquisition of camelina protein isolates (CPI) and sophia 
\nprotein isolates (SPI) through the application of traditional and ultrasonic-assisted 
\nextraction methods. We conducted a detailed examination of the protein isolates using 
\nsodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and explored 
\ntheir functional characteristics. It was notable that the application of ultrasonic extraction 
\nresulted in a substantial improvement in the functional properties of both camelina and 
\nsophia protein isolates, which included increased protein solubility, water holding capacity, 
\noil absorption capacity, as well as emulsifying and foaming properties. 
\nFurthermore, this study focused on using sophia and camelina seed meals to produce 
\nprotein hydrolysates through enzymatic processes (Alcalase and Flavourzyme). The 
\nantioxidant activities of these protein hydrolysates were examined using in vitro methods 
\nsuch as free radical scavenging activity, namely the 2,2’-azino-bis (3-ethylbenzothiazoline�6-sulfonic acid) (ABTS) radical cation, 2,2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl 
\nradical scavenging ability, and oxygen radical absorption capacity (ORAC) as well as 
\nreducing power and bioactivities such as inhibitory activities against the oxidation of LDL 
\ncholesterol and DNA strand breakage. In addition, bioinformatics methods were employed 
\nto predict bioactive peptides. The research mainly investigated to release of potent 
\nantioxidative, angiotensin-converting enzyme (ACE) inhibitory peptides and dipeptidyl 
\npeptidase IV (DPP IV) inhibitors using in silico approaches. The protein hydrolysates 
\nderived from sophia and camelina exhibited superior radical scavenging activity compared 
\nto protein isolates, particularly against DPPH and ABTS radicals. Especially in the case of 
\ncamelina peptide fractions, smaller-size peptides showed significantly higher radical 
\nscavenging activity and potency than larger-size peptides. The hydrolysates produced with 
\nthe Alcalase enzyme demonstrated the highest capacity for scavenging hydroxyl radicals 
\nand exhibited excellent oxygen radical absorbance capacity. Additionally, the hydrolysates 
\nshowed inhibitory effects on LDL cholesterol oxidation and protected against DNA damage 
\ncaused by hydroxyl and peroxyl radicals. The study successfully employed bioinformatics 
\nmethods to predict bioactive peptides, revealing that the selected peptides exhibited both 
\nACE and DPP IV inhibitory activities. Importantly, all resistant peptides to digestion were 
\nfound to be non-toxic. Furthermore, the in silico prediction based on physicochemical 
\nproperties and Lipinski's rule of five suggested that most peptides possess favorable drug�like properties. 
\nThese findings indicate that the protein isolates and hydrolysates derived from 
\ncamelina and sophia seed meal have desirable functional properties and exhibit antioxidant 
\nactivities. As a result, they are considered valuable sources of bioactive peptides for 
\ndeveloping available food ingredients and nutraceutical products. Therefore, 
\ncamelina/sophia protein hydrolysates show promise as functional food ingredients and 
\nnutraceuticals.

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction distillée sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.

score de la tête « metaresearch » (Codex)0,000
score de la tête « metaresearch » (Gemma)0,000
Version: codex-gemma-dda1882f352aStatut de validation: machine_predicted_unvalidated
Catégories candidatesMéta-épidémiologie (sens strict)
Catégories consensuellesaucune
DomaineSignal candidat: aucune · Signal consensuel: aucune
Devis d'étudeSignal candidat: Expérimental (laboratoire) · Signal consensuel: Expérimental (laboratoire)
GenreSignal candidat: Empirique · Signal consensuel: Empirique
Score de désaccord entre enseignants0,248
Score d'incertitude au seuil1,000

Scores Codex et Gemma par catégorie

CatégorieCodexGemma
Métarecherche0,0000,000
Méta-épidémiologie (sens strict)0,0000,000
Méta-épidémiologie (sens large)0,0010,000
Bibliométrie0,0010,001
Études des sciences et des technologies0,0010,001
Communication savante0,0000,001
Science ouverte0,0000,000
Intégrité de la recherche0,0010,001
Charge utile insuffisante (le modèle a refusé de juger)0,0000,000

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,023
Tête enseignante GPT0,217
Écart entre enseignants0,194 · la distance entre les deux têtes enseignantes sur ce seul travail
Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.

Devis d'étudeExpérimental (laboratoire)
Domainenon disponible
GenreEmpirique

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations0
Publié2023
Routes d'admission1
Résumé présentoui

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