Histone H4-K16 Acetylation Controls Chromatin Structure and Protein Interactions
2006· article· en· Science· Biochemistry, Genetics and Molecular Biology
aff
1 874
citations
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Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
2010· article· en· Nature Genetics· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
1 650
citations
Epigenetic protein families: a new frontier for drug discovery
2012· review· en· Nature Reviews Drug Discovery· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
1 308
citations
Regulation of Alternative Splicing by Histone Modifications
2010· article· en· Science· Biochemistry, Genetics and Molecular Biology
afffund
1 119
citations
MLL Targets SET Domain Methyltransferase Activity to Hox Gene Promoters
2002· article· en· Molecular Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
1 054
citations
Lysine Acetylation: Codified Crosstalk with Other Posttranslational Modifications
2008· review· en· Molecular Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
987
citations
EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
2013· article· en· Cancer Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
841
citations
Perceiving the epigenetic landscape through histone readers
2012· review· en· Nature Structural & Molecular Biology· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
834
citations
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET
2010· article· en· Nature· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
822
citations
Cotranscriptional Set2 Methylation of Histone H3 Lysine 36 Recruits a Repressive Rpd3 Complex
2005· article· en· Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
803
citations
The Paf1 Complex Is Required for Histone H3 Methylation by COMPASS and Dot1p: Linking Transcriptional Elongation to Histone Methylation
2003· article· en· Molecular Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
713
citations
Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II
2003· article· en· Molecular and Cellular Biology· Biochemistry, Genetics and Molecular Biology
aff
697
citations
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
2010· article· en· Blood· Biochemistry, Genetics and Molecular Biology
afffund
597
citations
Histone phosphorylation
2012· review· en· Epigenetics· Biochemistry, Genetics and Molecular Biology
afffund
596
citations
The diverse functions of histone acetyltransferase complexes
2003· review· en· Trends in Genetics· Biochemistry, Genetics and Molecular Biology
affsans résumé
576
citations
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape
2019· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affsans résumé
563
citations
The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
2011· article· en· Nature· Biochemistry, Genetics and Molecular Biology
fundno affsans résumé
558
citations
Bre1, an E3 Ubiquitin Ligase Required for Recruitment and Substrate Selection of Rad6 at a Promoter
2003· article· en· Molecular Cell· Biochemistry, Genetics and Molecular Biology
affsans résumé
534
citations
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
2011· article· en· Nature Chemical Biology· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
531
citations
Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth
2015· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affsans résumé
489
citations
A phosphatase complex that dephosphorylates γH2AX regulates DNA damage checkpoint recovery
2005· article· en· Nature· Biochemistry, Genetics and Molecular Biology
affsans résumé
477
citations
Non-histone protein methylation as a regulator of cellular signalling and function
2014· review· en· Nature Reviews Molecular Cell Biology· Biochemistry, Genetics and Molecular Biology
afffundsans résumé
475
citations
An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1
2013· article· en· ACS Chemical Biology· Biochemistry, Genetics and Molecular Biology
aff
466
citations
N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications
2018· article· en· Nature Neuroscience· Biochemistry, Genetics and Molecular Biology
afffund
456
citations
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
2015· article· en· Nature Medicine· Biochemistry, Genetics and Molecular Biology
affsans résumé
443
citations