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Record W105087476 · doi:10.1093/pch/16.6.e48

Horizontal transmission of group B streptococcus in a neonatal intensive care unit

2011· article· en· W105087476 on OpenAlexaff
Julia Morinis, Jay Shah, Prashanth Murthy, M Fulford

Bibliographic record

VenuePaediatrics & Child Health · 2011
Typearticle
Languageen
FieldMedicine
TopicNeonatal and Maternal Infections
Canadian institutionsMcMaster University
Fundersnot available
KeywordsMedicineGroup BNeonatal intensive care unitIncidence (geometry)Neonatal sepsisTransmission (telecommunications)PediatricsEtiologyPopulationSepsisNeonatal infectionStreptococcus agalactiaeStreptococcusDiseasePregnancyImmunologySurgeryInternal medicineBiology

Abstract

fetched live from OpenAlex

G roup B streptococcal (GBS) sepsis is a leading cause of mor- bidity and mortality in the neonatal population (1). A significant reduction has been seen in the incidence of early-onset GBS sepsis (defined as zero to seven days of age) from 1.7 cases per 1000 live births in 1993 to 0.31 cases per 1000 live births in 2005 (2). This reduction was due to the introduction of routine prenatal screening and maternal intrapartum antibiotic prophylaxis (2). However, the incidence of late-onset GBS disease (defined as seven to 89 days of age) has remained static and is now higher than early-onset GBS disease, averaging 0.35 cases per 1000 live births (1,2). The transmission of late-onset GBS sepsis is hypothesized to occur through multiple mechanisms such as persistent neonatal mucous membrane colonization, contamination of shared equipment via other infected neonates and through infected maternal breast milk (3-10). Currently, no preventive strategy has been shown to effectively reduce the incidence of late-onset GBS sepsis. The present case report describes probable acquisition of GBS disease through horizontal transmission in a neonatal intensive care unit based on the clinical and microbiological picture as well as the confirmation of strain based on antibiotic resistance patterns and pulsed-field gel electrophoresis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.235
Threshold uncertainty score0.588

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.281
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations26
Published2011
Admission routes1
Has abstractyes

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