Blood and Liver Antioxidant Capacity of Mice Fed High Fat Diet Supplemented with Digested Oat Bran Proteins
Bibliographic record
Abstract
The aim of this study was to assess the effect of three concentrations of oat bran protein hydrolysate (OPH) (1, 10, 10 mg/g diet) on oxidative stress marker in high fat fed animals. CD-1 male mice were placed into five groups and fed normal diet (ND), high fat (HF), and HF containing 1, 10, and 100 mg OPH/g of HF-diet for 3 weeks. Blood was collected at necropsy and analyze for glucose and markers of oxidative stress. At the highest level of OPH the oxygen radical absorbance capacity value of erythrocytes (123.1 ± 11.1 mMTrolox equivalents (TE)/mL blood) was higher (p < 0.05) than the value of HF group (96.5 ± 6.6 mM TE/mL) indicating higher scavenging activity that may be explained by higher thiol concentration detected. Liver superoxide dismutase (SOD) antioxidant enzyme activity was 13.2% lower in mice on HF-diet compared to those who received normal diet. Supplementation of HF-diet with OPH increased SOD activity to ND group level. OPH also had positive effect on respiratory exchange ratios but did not affect liver scavenging activity, calorie intake or bodyweight.In conclusion, addition OPH to HF diet increased radical scavenging activity in erythrocytes and SOD activity in mice liver samples.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".