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Record W141826081

A systematic review of the quality of publications reporting coronary artery bypass grafting trials.

2007· review· en· W141826081 on OpenAlexaff
Forough Farrokhyar, Rong Chu, Richard Whitlock, Lehana Thabane

Bibliographic record

VenuePubMed · 2007
Typereview
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsMcMaster University
Fundersnot available
KeywordsMedicineObservational studyRevascularizationRandomized controlled trialCardiopulmonary bypassAdverse effectBypass graftingCoronary artery diseaseArteryOff-pump coronary artery bypassIntensive care medicineInternal medicineCardiologyMeta-analysisMyocardial infarction
DOInot available

Abstract

fetched live from OpenAlex

OBJECTIVE: Several studies have shown that the quality of reports of randomized controlled trials (RCTs) in medicine is variable and often poor, whereas the quality of those in surgery is unknown. We aimed to assess the quality of reports of RCTs in coronary artery bypass grafting (CABG) surgery when comparing off- and on-pump techniques. METHODS: From electronic searches of MEDLINE, the Cochrane Library, CINAHL, HealthSTAR and EMBASE, we identified RCTs published between 2000 and 2005 comparing off- and on-pump CABG. We assessed the report quality, using 35 items from the Consolidated Standards for Reporting Trials (CONSORT) statement and 54 additional indicators relevant to CABG surgery. Some of the indicators comprised several small parts, making the maximum possible total score 105. Two authors independently reviewed and assessed the reporting quality of each RCT. The level of agreement was assessed with kappa statistics, and disagreements were resolved by consensus. We expressed descriptive analyses as median and interquartile range; we used a generalized estimating equation (GEE) for data analysis. RESULTS: We included 50 trials, for a total of 5134 patients. The kappa value was greater than 0.6 for 73 of 105 (70%) indicators. The overall report quality score varied from 35 to 93 of 105. The CONSORT score reporting quality varied from 16 to 39 of 42. The quality of reporting was poor and insufficient for the methods (particularly, the sample size, allocation and blinding subsections), results and discussion sections. With GEE modelling, the reporting quality had a strong association with trial size, publication year, trial location and funding source, but not with the results and type of primary outcome. CONCLUSION: The quality of the publications' reporting methods, results and discussion sections was suboptimal. It is critical that, in reporting surgical trials, authors follow the CONSORT guidelines as well as consider the surgical factors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.115
metaresearch head score (Gemma)0.419
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (broad)
Consensus categoriesnone
DomainCandidate signal: Reporting · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.985
Threshold uncertainty score0.610

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1150.419
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0150.009
Bibliometrics0.0470.036
Science and technology studies0.0020.003
Scholarly communication0.0070.006
Open science0.0030.004
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.931
GPT teacher head0.615
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSystematic review
DomainReporting
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations39
Published2007
Admission routes1
Has abstractyes

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