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Record W1419889091 · doi:10.1128/9781555818180.ch4

<i>Archaea</i>: Whose Sister Lineage?

2014· book-chapter· en· W1419889091 on OpenAlexaff
Robert L. Charlebois

Bibliographic record

VenueASM Press eBooks · 2014
Typebook-chapter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenomics and Phylogenetic Studies
Canadian institutionsCanadian Institute for Advanced ResearchUniversity of Ottawa
Fundersnot available
KeywordsArchaeaLineage (genetic)SisterEvolutionary biologyBiologyGenealogyGeneticsHistorySociologyBacteriaAnthropologyGene

Abstract

fetched live from OpenAlex

Following a review of archaeal genomics, the author wishes to scrutinize the convenient though perhaps misleading construct that is organismic phylogeny. In so doing, the author will address theories of the origin of eukaryotes, theories which look to Archaea for answers, thanks to the (largely) accepted rooting of the tree of life in the bacterial branch. Interest in archaeal genomes, as judged by volume in the literature, has focused mainly on the extremely halophilic archaea. The genetic instability appears to be prevalent not only among members of the family Halobacteriaceae but also among members of the order Sulfolobales, though the insertion sequences responsible are apparently unrelated. Physical analysis of archaeal nucleoids lags behind the efforts of genetic characterization. Rooting of the tree, using anciently duplicated paralogous sequences further divided Archaea from Bacteria by positioning the root in the bacterial branch. The biological species will tend to restrict lateral transfers to specific groups. However, movement of genes from more distantly related organisms is not precluded, even between Bacteria and Eucarya. Specific genomes have subsets of these collections and typically possess a number of open reading frames not found anywhere else. Sequence evolution is responsible for the unmatched open reading frames, having erased the evidence of their homologies. Confounding things further are lateral genetic transfer and gene replacement, especially from extinct lineages. Comparative genomic analyses have begun, and they will undoubtedly transform the method of molecular evolutionary study.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.837
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.228
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2014
Admission routes1
Has abstractyes

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