MétaCan
Menu
← Back to cohort
Record W146218102 · doi:10.1096/fasebj.21.6.a1076-b

Porcine jejunal alkaline phosphatase gene expression is quadratically changed during the postnatal growth examined by the quantitative real‐time RT‐PCR

2007· article· en· W146218102 on OpenAlexafffund
Tiejun Li, Chengbo Yang, Dale Lackeyram, Yulong Yin, Ming Fan

Bibliographic record

VenueThe FASEB Journal · 2007
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMolecular Biology Techniques and Applications
Canadian institutionsUniversity of Guelph
FundersNatural Sciences and Engineering Research Council of CanadaChinese Academy of Sciences
KeywordsAlkaline phosphataseReal-time polymerase chain reactionGene expressionBiologyHousekeeping geneEndocrinologyAndrologyWeaningInternal medicineJejunumMolecular biologyGeneEnzymeBiochemistryMedicine

Abstract

fetched live from OpenAlex

Intestinal alkaline phosphatase (AP) is responsible for hydrolyzing phosphoric ester bonds of organic compounds and likely plays a role in intestinal transcellular nutrient transport. This study was conducted to examine porcine jejunal AP gene expression (mRNA) during the postnatal growth. A total of 36 littermate purebred Yorkshire gilts were divided into six groups at the ages of d 1, 4, 6, 12, 20 (suckling) and 28 (1 wk post‐weaning), respectively. Relative jejunal AP mRNA abundance was measured by the real time RT‐PCR analysis (SmartCycler) using the SYBR Green‐I detection kit with glyceraldehydes‐3‐phosphate dehydrogenase (GAPDH) as the housekeeping gene. Orthogonal polynomial contrast analyses of the data showed a quadratic pattern (P=0.013) of the porcine jejunal AP mRNA expression (LSMEAN, 1.43, 2.50, 2.90, 4.32, 3.27 and 0.38, respectively, with a pooled SD=2.76) at the ages of d 1, 4, 6, 12 and 20, and 28. These results suggest that porcine jejunal alkaline phosphatase gene expression was increased from birth to the peak at 12‐d suckling and dramatically decreased during the weaning between d 21 and 28. Supported by the Chinese Academy of Sciences and NSERC.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.265
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes2
Has abstractyes

Explore more

Same venueThe FASEB Journal→Same topicMolecular Biology Techniques and Applications→French-language works237,207→