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A Cluster RCT Evaluating the Effect of Iodized Salt on Infant Development in Amhara Region of Ethiopia

2015· article· en· W1480140899 on OpenAlexaffabout
Husein Mohammed, Grace S. Marquis, Frances E. Aboud, Karim Bougma, Aregash Samuel

Bibliographic record

VenueThe FASEB Journal · 2015
Typearticle
Languageen
FieldMedicine
TopicInfant Development and Preterm Care
Canadian institutionsMcGill University
Fundersnot available
KeywordsIodised saltMicronutrientMedicineIodine deficiencyBayley Scales of Infant DevelopmentAnthropometryRandomized controlled trialIntervention (counseling)PediatricsEnvironmental healthCognitionPsychomotor learningInternal medicineThyroidPsychiatry

Abstract

fetched live from OpenAlex

Iodized has been associated with the physical and mental development of children. We examined the effects of iodized salt on the growth and mental development of infant. Forty‐four communities in the Amhara region were randomly assigned and had access to iodized salt early (intervention) or later through market forces (control). A total of 1220 pregnant women were recruited and their health and micronutrient status were assessed at enrollment. Data were collected on infants (2 to 13mo), including SES, diet, anthropometry, Hb, home stimulation and mental development (Bayley scales, Cognition, Expressive language, Receptive language and Fine motor scales). The median UI excretion was higher in the intervention vs controls, for both mothers during pregnancy (161 vs 121 µg/L, p<0.0001) and infants (141 vs 110 µg/L, p<0.02). Additionally, (45 vs 60%, p<0.05) of mothers and (37 vs 44%, p<0.05) of infants were iodine deficient. The intervention had a tendency to improve cognition with an effect size of 0.09, p=0.06, but did not affect the scores for the other three bayley scales. The intervention significantly improved home score (delta=0.45, p=0.04). Iodized salt intake improved iodine status of both pregnant women and their infants, and could lead to improved infant development. Funded by Micronutrients Initiative, Canada

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.330
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2015
Admission routes2
Has abstractyes

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