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Record W1491798713 · doi:10.3920/978-90-8686-760-8_35

Nucleotide sequence polymorphism of the growth hormone gene in American mink (Neovison vison)

2012· book-chapter· en· W1491798713 on OpenAlexaboutno aff
Jakub Skorupski, M. Kmieć

Bibliographic record

VenueWageningen Academic Publishers eBooks · 2012
Typebook-chapter
Languageen
FieldMedicine
TopicGrowth Hormone and Insulin-like Growth Factors
Canadian institutionsnot available
Fundersnot available
KeywordsMinkAmerican minkBiologyGeneticsPolymorphism (computer science)Single-nucleotide polymorphismGeneGrowth hormoneGenotypeHormoneEndocrinologyEcology

Abstract

fetched live from OpenAlex

The nucleotide sequence variation of the American mink (Neovison vison) growth hormone gene was analysed. For this purpose 1,113 bp region of the mink genomic DNA, encompassing four exons and three introns of somatotmropin gene, was amplified by nested-PCR and sequenced. The study included 116 individuals of wild mink (Nova Scotia, Canada), ranch mink (Scanblack, Wild, Sapphire, Pearl, Black Cross and Sapphire Cross; West Pomerania, Poland) and feral mink (Poland and Iceland). Sequencing allowed to determine the nucleotide composition of previously unrecognized non-coding regions, as well as exons and to identify 12 new SNP substitutions, one single nucleotide deletion and one ins/del polymorphism. The average incidence of SNPs in coding sequences was equal to 1/156.6 bp and in non-coding – 1/86.9 bp. Analysis of the observed number and location of substitutions revealed its non-random distribution and significant preponderance of transitions over transversions. The results also revealed a significant differences between originally wild mink and domesticated animals (both ranch and feral) in identified SNPs type and distribution. The results of the present study, supported by further analysis, can help in effective genetic monitoring of feral mink, as some differences were also found between ranch and feral mink.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.253
Teacher spread0.222 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2012
Admission routes1
Has abstractyes

Explore more

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