Jerusalem Artichoke as a Potential Prebiotic: Influence on Nutrient Utilization, Hindgut Fermentation and Immune Response of Labrador Dogs
Bibliographic record
Abstract
In order to explore the potential of Jerusalem artichoke (JA) as a prebiotic, four groups (CON, PRE-1, PRE-2 and PRE-3) of adult Labrador dogs (n=4 in each) were fed for 90d on a basal diet supplemented with pulverized JA tuber at 0, 1, 2 and 3% levels, respectively. Cell-mediated immunity was assessed on d56 by measuring skin indurations following intra-dermal phytohaemagglutinin-P inoculation. At d60, peripheral lymphocyte sub-populations in blood were assessed by flow cytometry. Humoral immunity was assessed by quantifying the antibody titre against sheep-RBC (SRBC). A digestion trial of 6d duration was conducted after 80d of feeding. Results revealed an increase (P=0.016) in skin indurations in PRE1 and PRE-2 compared to CON and PRE-3. There was no impact of JA on circulating peripheral CD3+ and CD8+ populations, however, CD4+ populations enhanced (P=0.005) in JA supplemented groups than CON. The antibody titre (log2) against SRBC was also higher (P=0.007) in treatment groups than control. There was an increase (P≤0.05) in faecal concentration of lactate and short-chain fatty acids with a concomitant reduction in ammonia. The faecal counts (log10 cfu/g) of health-positive Bifidobacterium (P=0.035) and Lactobacillus (P=0.062) were higher in treatment groups while health-negative coliforms and Clostridium counts remained unaltered. The digestion trial indicated that JA supplementation improved the digestibility of fibre (P=0.003) along with that of calcium and phosphorus. Overall findings revealed that JA may constitute a perspective prebiotic additive because of its apparent positive impacts on immune status as well as hindgut fermentation.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".