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Detection of Infectious <i>Cryptosporidium</i> in Filtered Drinking Water

2004· article· en· W1494391862 on OpenAlexaff
Ramon Aboytes, George di Giovanni, Felicia A. Abrams, Corey Rheinecker, W.J. McElroy, Nancy E. Shaw, Mark W. LeChevallier

Bibliographic record

VenueAmerican Water Works Association · 2004
Typearticle
Languageen
FieldImmunology and Microbiology
TopicParasitic Infections and Diagnostics
Canadian institutionsAmerican Water (Canada)
FundersTexas State University
KeywordsCryptosporidiumCryptosporidium parvumWater qualityWater treatmentBiologyVeterinary medicineGenotypePolymerase chain reactionSurface waterMicrobiologyFecesEnvironmental scienceMedicineEnvironmental engineeringEcology

Abstract

fetched live from OpenAlex

Monitoring of 82 surface water treatment plants revealed that 1.4% of 1,690 100‐L finished water samples tested positive for infectious Cryptosporidium using the cell culture‐polymerase chain reaction). Infectious oocysts were detected in finished water samples from 22 water treatment plants (26.8%). Genotype analysis identified 23 isolates as Cryptosporidium parvum and one isolate as Cryptosporidium hominis. All isolates subgenotyped were shown to be genetically distinct environmental isolates. Analysis of the water quality and treatment plant characteristics showed no differences between the positive and negative sites. More than 70% of the positive samples occurred in filtered water samples of <0.1 ntu, and 20% of the positive samples were in water of <0.05 ntu. There was no association among Cryptosporidium occurrence and source water type, microbial indicators, or plant operation and treatment. It was concluded that given sufficient testing, nearly all conventional treatment plants would be at risk for passing infectious oocysts. Based on this study, the overall risk of Cryptosporidium infection for conventionally treated drinking water was 52 infections/10,000 people/year, with an 80% credible range of 9–119 infections/10,000 people/year. It was also concluded based on these studies that conventional treatment requires an additional treatment barrier, such as ultraviolet light disinfection, to meet the US Environmental Protection Agency risk goals.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.209
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations56
Published2004
Admission routes1
Has abstractyes

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