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Histological characterization of soft‐embalmed porcine tendon and muscle (914.1)

2014· article· en· W1495700860 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueThe FASEB Journal · 2014
Typearticle
Languageen
FieldMedicine
TopicMusicians’ Health and Performance
Canadian institutionsQueen's University
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health Research
KeywordsEmbalmingSoft tissueAnatomyTendonMedicineMasson's trichrome stainTrichromeStainingPathologyH&E stain

Abstract

fetched live from OpenAlex

Embalmed material is used in many fields because of its benefits over fresh materials; however, typical formalin‐fixation results in materials that are vastly different from their original state. Soft‐embalming has received recognition as a viable alternative to fresh or formalin‐fixed materials in education and research, especially in orthopedics. Soft‐embalmed tissue has mainly been characterized by gross features, with minimal investigation into the microscopic features of different types of soft‐embalmed tissues. Deep flexor muscle and tendon were harvested from porcine forelimbs. Samples were soft‐embalmed using one of three different methods: phenol‐based, phenoxyethanol‐based, and Thiel embalming. The samples were visualized using Masson’s trichrome staining immediately following embalming and three weeks later. All types of soft‐embalming displayed typical tendon structural characteristics at both time points. The staining of the tendons ranged from almost entirely blue, as would be expected, to almost entirely red, which was unexpected, depending on the treatment. All soft‐embalmed muscle samples exhibited typical colouring, but there were structural differences. At both time points, muscle of phenol‐based and phenoxyethanol‐based embalming generally exhibited normal muscle structure, while Thiel‐embalmed muscle appeared to have suffered degradation. This histological analysis is a step forward in understanding the effects of different soft‐embalming methods on different tissues, which can aid in determining their efficacy. Grant Funding Source : This research was supported in part by NSERC and CIHR

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.916
Threshold uncertainty score0.219

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.259
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it