Effect of long‐term increase in the frequency and/or prolongation of dialysis duration on certain clinical manifestations and results of laboratory investigations in patients with chronic renal failure
Bibliographic record
Abstract
The effects of dialysis frequency increase by one weekly and prolongation of dialysis duration by a mean of 17.5% on certain clinical manifestation and results of laboratory investigations were studied in a group of 14 patients treated with haemodialyses because of chronic renal failure caused by isolated renal diseases. Haemodialyses were carried out using a RSP Travenol artificial kidney and Ultra Flo 145 dialysers. The blood flow was always 200 ml/min and the flow of dialysing fluid was 500 ml/min. One dialyser was used repeatedly during 3 weeks in the same patients. After increasing the frequency or duration of dialyses the patients were not given transfusions of blood donors. The mean length of observation after increasing the frequency of dialyses was 6.4 months and after increasing their duration this length was 6.9 months. The change in the mode of dialysis had no significant effect on the concentration of urea and creatinine before as well as after dialysis. The increase in the frequency of dialyses caused a significant rise in the value of haematocrit by nearly 4%, a rise in the serum albumin concentration by a mean of 0.45 g/100 ml; a mean rise in the velocity of nerve conduction by over 6% of the lower normal range, and a mean rise in dry body weight by nearly 3.5 kg. Prolongation of dialysis time caused a significant mean rise in the haematorcrit value by over 1% before dialysis and in the serum albumin level by a mean of 0.30 g/100 ml. Both, the increase in the frequency and in the duration of dialyses caused a fall in the arterial blood pressure in hypertensive patients. The very favourable effects of increased frequency of dialyses on the clinical state of patients and on important laboratory parameters suggests that in near future the basic form of treatment of chronic renal failure may be daily short-lasting haemodialysis.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".