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Record W1519684562 · doi:10.1002/9780470514023.ch10

Optical Causes of Experimental Myopia

2007· review· en· W1519684562 on OpenAlexaff
J. G. Sivak, D. L. Barrie, M.G. Callender, Michael J. Doughty, Ruth L. Pickett Seltner, J. A. West

Bibliographic record

VenueNovartis Foundation symposium · 2007
Typereview
Languageen
FieldMedicine
TopicCorneal surgery and disorders
Canadian institutionsUniversity of Waterloo
Fundersnot available
KeywordsEmmetropiaDioptreVitreous chamberAccommodationLens (geology)Refractive errorCorneaRetinalOphthalmologyOptometryOpticsMedicineVisual acuityPhysics

Abstract

fetched live from OpenAlex

Experiments in which chicks are reared wearing a translucent goggle, or some similar device designed to degrade the retinal image, usually result in the induction of a significant degree of myopia. The induced myopia is due to enlargement of the vitreous chamber of the eye. Despite extensive change in the size, shape and refractive index distribution of the crystalline lens, its refractive power is static in the embryonic and early chick eye. The contribution to myopia of the cornea is uncertain; some studies have indicated either an increase or a decrease in corneal radius of curvature while others found no change. The fact that experimental myopia can be produced in chicks even when the optic nerve has been cut or when the degraded retinal image is restricted to one sector of the eye suggests that accommodation is not involved. Nevertheless, when the retinal image is degraded by being defocused with convex or concave lenses, myopia (concave lenses) or hyperopia (convex lenses) results. Chicks wearing concave or convex soft contact lenses from the day of hatching develop refractive states equal to the lens power (+8 and -10 diopters) within one week. The ability of the eye to vary its refractive development according to the sign of defocus suggests a role for accommodation. However, study of the ciliary muscle and accommodative apparatus of myopic and emmetropic chick eyes does not reveal any morphological differences that might indicate that the myopic eye had experienced an increased level of accommodation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.004
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.101
GPT teacher head0.405
Teacher spread0.304 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations33
Published2007
Admission routes1
Has abstractyes

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